Publications of the Week Motif-Driven Interactions between RNA and PRC2 Are Rheostats that Regulate Transcription Elongation Rosenberg, M., et al. | January 5, 2021 Although polycomb repressive complex 2 (PRC2) is now recognized as an RNA-binding complex, the full…eabramovichJanuary 5, 2021 Read More
Publications of the Week SPRED1 Deletion Confers Resistance to MAPK Inhibition in Melanoma Ablain, J., et al. | December 18, 2020 Functional evaluation of genetic lesions can discover a role in cancer initiation and progression and…eabramovichDecember 18, 2020 Read More
Publications of the Week Dynamics of RNA Polymerase II and Elongation Factor Spt4/5 Recruitment during Activator-Dependent Transcription Rosen, G.A., et al. | December 16, 2020 The synthesis of a eukaryotic messenger RNA molecule involves the association of RNA polymerase and…eabramovichDecember 16, 2020 Read More
Publications of the Week A Macrophage-Specific lncRNA Regulates Apoptosis and Atherosclerosis by Tethering HuR in the Nucleus Simion, V., et al. | December 11, 2020 The authors identified a lncRNA termed MAARS that is expressed specifically in macrophages in atherosclerotic…eabramovichDecember 11, 2020 Read More
Publications of the Week Direct Tumor Killing and Immunotherapy through Anti-SerpinB9 Therapy Jiang, L., et al. | December 7, 2020 The authors found that serpin B9 (Sb9) prevents cancer cells from killing themselves due to…eabramovichDecember 7, 2020 Read More
Publications of the Week Tolerogenic Nanoparticles Suppress Central Nervous System Inflammation Kenison, J.E., et al. | December 4, 2020 The authors developed a novel nanomaterial-based approach for antigen-specific immune modulation. This novel approach allows…eabramovichDecember 4, 2020 Read More
Publications of the Week Shigella flexneri Disruption of Cellular Tension Promotes Intercellular Spread Duncan-Lowey, J.K., et al. | December 2, 2020 The findings in this publication demonstrate that the gram-negative intracellular bacterial pathogen Shigella flexneri, which…eabramovichDecember 2, 2020 Read More
Publications of the Week Endogenous Antisense RNA Curbs CD39 Expression in Crohn’s Disease Harshe, R.P., et al. | November 27, 2020 CD39 is an ectonucleotidase that initiates conversion of extracellular nucleotides into immunosuppressive adenosine. CD39 is…eabramovichNovember 27, 2020 Read More
Publications of the Week Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2 Hekman, R.M., et al. | November 24, 2020 The authors investigated the pathways hijacked by the SARS-CoV-2 cells in human alveolar cells during…eabramovichNovember 24, 2020 Read More
Publications of the Week Rev7 Loss Alters Cisplatin Response and Increases Drug Efficacy in Chemotherapy-Resistant Lung Cancer Vassel, F.M., et al. | November 20, 2020 Mutagenic translesion synthesis (TLS) allows cells to increase their survival after DNA damage by bypassing…eabramovichNovember 20, 2020 Read More