Publications of the Week

Genetic studies of human embryonic morphogenesis are constrained by ethical and practical challenges, restricting insights…

Interferon regulatory factor 4 (IRF4) is an oncogenic transcription factor (TF) in several hematological malignancies.…

Genes in many bacteria are rich in purine nucleotides (A and G), but the origin…

Endogenous retroviral (ERV) RNA is highly expressed in cancer, suggesting a selective advantage. We identify…

Studying the genetic basis of human phenotypes involves two primary strategies. Model-system experiments generate interpretable…

Engineering the genetic code—by reassigning multiple of the 64 natural codons—enables making organisms resistant to…

Prime editing is a versatile clinical genome editing method that enables precise substitutions, small insertions…

Drug delivery to the oesophagus poses unique challenges, including rapid transit time due to gravity…

Enteric pathogens are a major contributor to the global disease burden, necessitating vaccines capable of…

Although the gut microbiome is implicated in colorectal cancer (CRC), microbiome and metabolome alterations along…