Publications of the Week Hyperactivation of Sympathetic Nerves Drives Depletion of Melanocyte Stem CellsZhang, B., et al. | January 23, 2020Empirical and anecdotal evidence has associated stress with accelerated hair greying (formation of unpigmented hairs),…sciencecityJanuary 23, 2020 Read More
Publications of the Week Mechanism of Adrenergic CaV1.2 Stimulation Revealed by Proximity ProteomicsLiu, G., et al. | January 23, 2020Increased cardiac contractility during the fight-or-flight response is caused by β-adrenergic augmentation of CaV1.2 voltage-gated…sciencecityJanuary 23, 2020 Read More
Publications of the Week Increased Expression of Schizophrenia-Associated Gene C4 Leads to Hypoconnectivity of Prefrontal Cortex and Reduced Social InteractionComer, A., L., et al. | January 22, 2020Schizophrenia is a severe mental disorder with an unclear pathophysiology. Increased expression of the immune…sciencecityJanuary 22, 2020 Read More
Publications of the Week Targeting Rictor Sensitizes SMAD4-Negative Colon Cancer to IrinotecanWong, C., K., et al. | January 15, 2020Deciphering molecular targets to enhance sensitivity to chemotherapy is becoming a priority for effectively treating…sciencecityJanuary 15, 2020 Read More
Publications of the Week Generation of Mesenchyme Free Intestinal Organoids from Human Induced Pluripotent Stem CellsMithal, A., et al. | January 14, 2020Efficient generation of human induced pluripotent stem cell (hiPSC)-derived human intestinal organoids (HIOs) would facilitate…sciencecityJanuary 14, 2020 Read More
Publications of the Week Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVSChao C., et al. | January 13, 2020My lab is focused on the identification of molecular mechanisms by which the environment, the…sciencecityJanuary 13, 2020 Read More
Publications of the Week In Vitro Characterization of the Human Segmentation ClockDiaz-Cuadros, M., et al. | January 10, 2020The segmental organization of the vertebral column is established early in embryogenesis, when pairs of…sciencecityJanuary 10, 2020 Read More
Publications of the Week Selective Induction of Antibody Effector Functional Responses Using MF59-Adjuvanted VaccinationBoudreau, C., M., et al. | January 8, 2020Seasonal and pandemic influenza infection remains a major public health concern worldwide. Driving robust humoral…sciencecityJanuary 8, 2020 Read More
Publications of the Week C-Cbl Targets PD-1 in Immune Cells for Proteasomal Degradation and Modulates Colorectal Tumor GrowthLyle, C., et al. | January 6, 2020Casitas B lymphoma (c-Cbl) is an E3 ubiquitin ligase and a negative regulator of colorectal…sciencecityJanuary 6, 2020 Read More
Publications of the Week IL-33 Signaling Alters Regulatory T Cell Diversity in Support of Tumor DevelopmentLi, A., et al. | December 20, 2019Regulatory T cells (Tregs) can impair anti-tumor immune responses and are associated with poor prognosis in…sciencecityDecember 20, 2019 Read More