Publications of the Week

Histones are rapidly loaded on the HSV genome upon entry into the nucleus of human…

Pancreatic ductal adenocarcinoma (PDAC) has a collagen-rich dense extracellular matrix (ECM) that promotes malignancy of…

As organelles of the innate immune system, inflammasomes activate caspase-1 and other inflammatory caspases that…

FOXP3 deficiency in mice and in patients with immune dysregulation polyendocrinopathy enteropathy X-linked (IPEX) syndrome results…

Toxin-antitoxin (TA) systems are widespread in bacteria, but their activation mechanisms and bona fide targets…

MicroRNAs (miRNA) are known to regulate expression of genes involved in several physiological processes including…

Chemokines are chemotactic cytokines that regulate the migration of immune cells. Chemokines function as cues…

Microglial-derived inflammation has been linked to a broad range of neurodegenerative and neuropsychiatric conditions, including…

Regulatory B cells contribute to the regulation of immune responses in cancer, autoimmune disorders, allergic…

Depletion of architectural factors globally alters chromatin structure but only modestly affects gene expression. We revisit the…