Publications of the Week Actin-Related Protein (Arp) 2/3 Complex Plays a Critical Role in the Aquaporin-2 Exocytotic Pathway Liu, C.-C. S., et al. | July 16, 2021 The trafficking of proteins such as aquaporin-2 (AQP2) in the exocytotic pathway requires an active…pthomsonJuly 16, 2021 Read More
Publications of the Week Nephrotoxicity Assessment with Human Kidney Tubuloids using Spherical Nucleic Acid-Based mRNA Nanoflares Wiraja, C., et al. | July 14, 2021 Drug-induced nephrotoxicity represents an important cause of acute kidney injury with associated patient morbidity and…pthomsonJuly 14, 2021 Read More
Publications of the Week Expansion of Tumor-Associated Treg Cells upon Disruption of a CTLA-4-Dependent Feedback Loop Marangoni, F., et al. | July 7, 2021 This week we profile a recent publication in Cell from Dr. Thorsten Mempel's lab at…pthomsonJuly 7, 2021 Read More
Publications of the Week Tick-Over Mediated Complement Activation Is Sufficient to Cause Basal Deposit Formation in Cell-Based Models of Macular Degeneration Chinchilla, B., et al. | July 6, 2021 This week we profile a recent publication in the Journal of Pathology from Dr. Rosario…pthomsonJuly 6, 2021 Read More
Publications of the Week Plasma from Patients with Bacterial Sepsis or Severe COVID-19 Induces Suppressive Myeloid Cell Production from Hematopoietic Progenitors In Vitro Reyes, M., et al. | July 2, 2021 Patients with bacterial sepsis or severe COVID-19 have increased numbers of suppressive myeloid cells in…pthomsonJuly 2, 2021 Read More
Publications of the Week Fatty Acids Activate the Transcriptional Coactivator YAP1 to Promote Liver Fibrosis via p38 Mitogen-Activated Protein Kinase Salloum, S., et al. | July 1, 2021 Patients with simple steatosis (SS) and nonalcoholic steatohepatitis can develop progressive liver fibrosis, which is…pthomsonJuly 1, 2021 Read More
Publications of the Week Microbiota-Derived Acetate Activates Intestinal Innate Immunity via the Tip60 Histone Acetyltransferase Complex Jugder, B.-E., et al. | June 28, 2021 Enteroendocrine cells are rare intestinal cells that respond to microbial metabolites. Dr. Paula Watnick’s laboratory…pthomsonJune 28, 2021 Read More
Publications of the Week Design Considerations for Macroencapsulation Devices for Stem Cell Derived Islets for the Treatment of Type 1 Diabetes Goswami, D., et al. | June 24, 2021 Stem cell derived insulin producing cells or islets have shown promise in reversing Type 1…pthomsonJune 24, 2021 Read More
Publications of the Week Systemic and Mucosal Mobilization of Granulocyte Subsets during Lentiviral Infection Jones, R., & Manickam, C., et al. | June 21, 2021 The Reeves laboratories are focused on understanding the role of innate immune cells in modulating…pthomsonJune 21, 2021 Read More
Publications of the Week Induction of Antigen-Specific Tolerance by Nanobody–Antigen Adducts That Target Class-II Major Histocompatibility Complexes Pishesha, N., et al. | June 18, 2021 The association of autoimmune diseases with particular allellic products of the class-II major histocompatibility complex…sciencecityJune 18, 2021 Read More