Publications of the Week Autonomous Lipid Nanoparticle Engineering Sagmeister, P., et al. | October 8, 2026 Lipid nanoparticles (LNPs) are the leading vehicles for encapsulating and delivering nucleic acid therapeutics. Yet,…karnottOctober 8, 2026 Read More
Publications of the Week Phase 1 Study of Anito-cel, a d-Domain BCMA CAR T Cell for Refractory or Recurrent Myeloma Frigault, M., et al. | October 6, 2026 Anitocabtagene autoleucel (anito-cel), a B-cell maturation antigen (BCMA)–directed autologous chimeric antigen receptor (CAR) T-cell therapy…karnottOctober 6, 2026 Read More
Publications of the Week Ceramide Synthesis Mediates Colorectal Cancer Metastasis Through a YAP-Driven Regenerative Program Goswami, S., et al. | October 1, 2026 Ceramides are a class of sphingolipid molecules involved in cell survival, stress responses, and skin…karnottOctober 1, 2026 Read More
Publications of the Week The Molecular Landscape of Hypertrophic Cardiomyopathy Across Disease Stages and Genotypes Adami, E., et al. | September 28, 2026 Hypertrophic cardiomyopathy (HCM) is marked by asymmetric cardiac wall thickening, hypercontractility, diastolic dysfunction, and fibrosis.…karnottSeptember 28, 2026 Read More
Publications of the Week Pyridoxal-Phosphate-Dependent Biosynthesis of Aminovaleramide by AvaS in tRNA Sun, J., et al. | September 25, 2026 In eubacteria, decoding of isoleucine codon AUA requires a specialized tRNA (tRNAIle2) modified with lysidine…karnottSeptember 25, 2026 Read More
Publications of the Week Maintaining Transcriptome Solubility Constrains mRNA Sequence Composition Todisco, M., et al. | September 22, 2026 RNA base-pairing enables folding and regulation, but it also creates pervasive opportunities for unintended RNA–RNA…karnottSeptember 22, 2026 Read More
Publications of the Week EBV Reactivation Priming of the Peripheral Immune System in Multiple Sclerosis Relapse King, D., et al. | September 18, 2026 Despite decades of research, the cellular and molecular events preceding multiple sclerosis (MS) relapse remain…karnottSeptember 18, 2026 Read More
Publications of the Week Immortalized Smooth Muscle Cells Enhance In Vitro Vasculogenesis Nikmaneshi, M., et al. | September 16, 2026 De novo vessel formation (vasculogenesis) in vitro is a key step in tissue engineering to…karnottSeptember 16, 2026 Read More
Publications of the Week Cyclin E-CDK2 Regulates Cancer Cell Transcriptional Program and Response to Immunotherapy Through BRD4 Chu, C., et al. | September 11, 2026 The cyclin E-cyclin-dependent kinase 2 (CDK2) complex is a component of mammalian cell-cycle machinery that…karnottSeptember 11, 2026 Read More
Publications of the Week Loss of Function of ALDH3B2 Transdifferentiates Human Pancreatic Duct Cells Into β-Like Cells Li, J., et al. | September 9, 2026 Replenishment of pancreatic β cells is key to a cure for diabetes. β cell regeneration…karnottSeptember 9, 2026 Read More