Publications of the Week Targeted Therapies Prime Oncogene-Driven Lung Cancers for Macrophage-Mediated DestructionVaccaro, K., et al. | April 19, 2024Macrophage immune checkpoint inhibitors, such as anti-CD47 antibodies, show promise in clinical trials for solid…karnottApril 19, 2024 Read More
Publications of the Week Episymbiotic Saccharibacteria TM7x Modulates the Susceptibility of Its Host Bacteria to Phage Infection and Promotes Their CoexistenceZhong, Q., et al. | April 15, 2024The factors influencing the interaction between phages and bacteria, as well as their long-term coexistence,…karnottApril 15, 2024 Read More
Publications of the Week Discovery of Antibiotics That Selectively Kill Metabolically Dormant BacteriaZheng, E., et al. | April 10, 2024There is a need to discover and develop non-toxic antibiotics that are effective against metabolically…karnottApril 10, 2024 Read More
Publications of the Week Direct Interrogation of Context-Dependent GPCR Activity with a Universal Biosensor PlatformJanicot, R., et al. | April 8, 2024G protein-coupled receptors (GPCRs) are the largest family of druggable proteins encoded in the human…karnottApril 8, 2024 Read More
Publications of the Week Gut Microbiome and Metabolome Profiling in Framingham Heart Study Reveals Cholesterol-Metabolizing BacteriaLi, C., et al. | April 4, 2024Accumulating evidence suggests that cardiovascular disease (CVD) is associated with an altered gut microbiome. Our…karnottApril 4, 2024 Read More
Publications of the Week Skin Biopsy Detection of Phosphorylated α-Synuclein in Patients with SynucleinopathiesGibbons, C., et al. | April 3, 2024Can skin biopsy detect phosphorylated α-synuclein in individuals with synucleinopathies such as Parkinson disease (PD),…karnottApril 3, 2024 Read More
Publications of the Week Neutrophils Bearing Adhesive Polymer Micropatches as a Drug-Free Cancer ImmunotherapyKumbhojkar, N., et al. | April 2, 2024Tumour-associated neutrophils can exert antitumour effects but can also assume a pro-tumoural phenotype in the…karnottApril 2, 2024 Read More
Publications of the Week A Noncoding Regulatory Variant in IKZF1 Increases Acute Lymphoblastic Leukemia Risk in Hispanic/Latino Childrende Smith, A., et al. | March 28, 2024Hispanic/Latino children have the highest risk of acute lymphoblastic leukemia (ALL) in the US compared…karnottMarch 28, 2024 Read More
Publications of the Week Derivation and External Validation of a Simple Risk Score for Predicting Severe Acute Kidney Injury After Intravenous Cisplatin: Cohort StudyGupta, S., et al. | March 27, 2024The primary outcome was CP-AKI, defined as a twofold or greater increase in serum creatinine…karnottMarch 27, 2024 Read More
Publications of the Week Branched Chemically Modified Poly(A) Tails Enhance the Translation Capacity of mRNAChen, H., et al. | March 25, 2024Although messenger RNA (mRNA) has proved effective as a vaccine, its potential as a general…karnottMarch 25, 2024 Read More