Publications of the Week Cellular and Molecular Basis of PfCoronin Function in Artemisinin Resistance in Plasmodium falciparum Ullah, I., et al. | August 4, 2026 Artemisinin combination therapies are central to malaria control, but their efficacy is threatened by the…karnottAugust 4, 2026 Read More
Publications of the Week CDK8 Inhibition Releases the Muscle Differentiation Block in Fusion-Driven Alveolar Rhabdomyosarcoma Zhang, S., et al. | July 29, 2026 Alveolar rhabdomyosarcoma (aRMS) is a fusion-driven pediatric cancer with poor survival and limited therapeutic options.…karnottJuly 29, 2026 Read More
Publications of the Week Non-Genotoxic Transplantation and In Vivo Selection Through Epitope Editing Casirati, G., et al. | July 27, 2026 In a recent Nature publication, Dr. Gabriele Casirati, Dr. Andrea Cosentino, and colleagues in the…karnottJuly 27, 2026 Read More
Publications of the Week Two Distinct SWI/SNF Complexes Direct Chromatin-Linked Transcriptional Programs in Toxoplasma Schwarz, D., et al. | July 22, 2026 Chromatin remodeling complexes dynamically modify DNA accessibility to regulate gene expression during eukaryotic cell cycle…karnottJuly 22, 2026 Read More
Publications of the Week A Viral ORFeome Library for Systems-Level Genetic Dissection of Host-Pathogen Interactions Fujimura, E., et al. | July 17, 2026 Virological research has traditionally focused on individual viruses or viral families. Advances in DNA synthesis…karnottJuly 17, 2026 Read More
Publications of the Week Arrayed Single-Gene Perturbations Identify Drivers of Human Anterior Neural Tube Closure Huang, R., et al. | July 14, 2026 Genetic studies of human embryonic morphogenesis are constrained by ethical and practical challenges, restricting insights…karnottJuly 14, 2026 Read More
Publications of the Week Pharmacological Targeting of IRF4 as a Therapeutic Strategy for Multiple Myeloma Agius, M., et al. | July 9, 2026 Interferon regulatory factor 4 (IRF4) is an oncogenic transcription factor (TF) in several hematological malignancies.…karnottJuly 9, 2026 Read More
Publications of the Week Purine Bias in Bacterial Genes Is Driven by Runaway Transcription Dierksheide, K., et al. | July 7, 2026 Genes in many bacteria are rich in purine nucleotides (A and G), but the origin…karnottJuly 7, 2026 Read More
Publications of the Week Recurrent ZC3H18 Mutations Stabilize Oncogenic Endogenous Retroviral RNA Tanu, T., et al. | July 2, 2026 Endogenous retroviral (ERV) RNA is highly expressed in cancer, suggesting a selective advantage. We identify…karnottJuly 2, 2026 Read More
Publications of the Week NERINE Reveals Rare Variant Associations in Gene Networks Across Phenotypes and Implicates an SNCA-PRL-LRRK2 Subnetwork in Parkinson’s Disease Nazeen, S., et al. | June 30, 2026 Studying the genetic basis of human phenotypes involves two primary strategies. Model-system experiments generate interpretable…karnottJune 30, 2026 Read More