Publications of the Week

Development often relies on molecular prepatterning over large tissue scales, and how these patterns emerge…

Macrophages are critical effectors of antibody therapies for lymphoma, but the best targets to engage…

Using a human breast organoid high-content screening platform, we show that defined chemical mixtures induce…

A comprehensive cell fate map of mammalian embryogenesis has remained out of reach given the…

Targeted lipid nanoparticles (LNPs) offer a nonviral approach for in vivo cell engineering but efficient…

Lipid nanoparticles (LNPs) are the leading vehicles for encapsulating and delivering nucleic acid therapeutics. Yet,…

Anitocabtagene autoleucel (anito-cel), a B-cell maturation antigen (BCMA)–directed autologous chimeric antigen receptor (CAR) T-cell therapy…

Ceramides are a class of sphingolipid molecules involved in cell survival, stress responses, and skin…

Hypertrophic cardiomyopathy (HCM) is marked by asymmetric cardiac wall thickening, hypercontractility, diastolic dysfunction, and fibrosis.…

In eubacteria, decoding of isoleucine codon AUA requires a specialized tRNA (tRNAIle2) modified with lysidine…