Publications of the Week Integrating CD4+ T Cell Help for Therapeutic Cancer Vaccination in a Preclinical Head and Neck Cancer Model Shibata, H., et al. | August 20, 2021 Head and neck squamous cell carcinomas (HNSCC) are well suited for cancer vaccination strategies. In…pthomsonAugust 20, 2021 Read More
Publications of the Week Human Sensorimotor Organoids Derived from Healthy and Amyotrophic Lateral Sclerosis Stem Cells Form Neuromuscular Junctions Pereira, J. D., et al. | August 20, 2021 Human induced pluripotent stem cells (iPSC) hold promise for modeling diseases in individual human genetic…pthomsonAugust 20, 2021 Read More
Publications of the Week FHL2 Anchors Mitochondria to Actin and Adapts Mitochondrial Dynamics to Glucose Supply Basu, H., et al. | August 13, 2021 Mitochondrial movement and distribution are fundamental to their function. Here we report a mechanism that…pthomsonAugust 13, 2021 Read More
Publications of the Week Yap/Taz Inhibit Goblet Cell Fate to Maintain Lung Epithelial Homeostasis Hicks-Berthet, J., et al. | August 9, 2021 Read the Publication This week we profile a recent publication in Cell Reports from Dr.…pthomsonAugust 9, 2021 Read More
Publications of the Week Genes with Specificity for Expression in the Round Cell Layer of the Growth Plate Are Enriched in Genomewide Association Study (GWAS) of Human Height Renthal, N. E., and Nakka, P., et al. | August 6, 2021 Human adult height reflects the outcome of childhood skeletal growth. Growth plate (epiphyseal) chondrocytes are…pthomsonAugust 6, 2021 Read More
Publications of the Week Neurotensin Is an Anti-Thermogenic Peptide Produced by Lymphatic Endothelial Cells Li, J., et al. | August 2, 2021 Dr. Evan Rosen's lab is focused on understanding how adipose tissue functions normally, and how…pthomsonAugust 2, 2021 Read More
Publications of the Week Dynamic BH3 Profiling Identifies Active BH3 Mimetic Combinations in Non-Small Cell Lung Cancer Potter, D. S., et al. | July 30, 2021 Conventional chemotherapy is still of great utility in oncology and rationally constructing combinations with it…pthomsonJuly 30, 2021 Read More
Publications of the Week cGAS-Like Receptors Sense RNA and Control 3′2′-cGAMP Signaling in Drosophila Slavik, K. M., et al. | July 27, 2021 Cyclic GMP–AMP synthase (cGAS) is a cytosolic DNA sensor that produces the second messenger 2′3′-cGAMP…pthomsonJuly 27, 2021 Read More
Publications of the Week Extracellular Domain Shedding of the ALK Receptor Mediates Neuroblastoma Cell Migration Huang, H., et al. | July 22, 2021 Although activating mutations of the anaplastic lymphoma kinase (ALK) membrane receptor occur in ∼10% of…pthomsonJuly 22, 2021 Read More
Publications of the Week Haplotype-Resolved Germline and Somatic Alterations in Renal Medullary Carcinomas Tan, K.-T., et al. | July 21, 2021 Renal medullary carcinomas (RMCs) are rare kidney cancers that occur in adolescents and young adults…pthomsonJuly 21, 2021 Read More