Publications of the Week A Generalized HIV Vaccine Design Strategy for Priming of Broadly Neutralizing Antibody ResponsesSteichen, J., M., et al. | November 7, 2019Vaccine induction of broadly neutralizing antibodies (bnAbs) to human immunodeficiency virus (HIV) remains a major…sciencecityNovember 7, 2019 Read More
Publications of the Week Genotype-Fitness Maps of EGFR-Mutant Lung Adenocarcinoma Chart the Evolutionary Landscape of Resistance for Combination Therapy OptimizationBolan, P., O., et al. | October 30, 2019Cancer evolution poses a central obstacle to cure, as resistant clones expand under therapeutic selection…sciencecityOctober 30, 2019 Read More
Publications of the Week Fibroblastic Reticular Cells Enhance T Cell Metabolism and Survival via Epigenetic RemodelingBrown, F., D., et al. | October 28, 2019Lymph node fibroblastic reticular cells (FRCs) respond to signals from activated T cells by releasing…sciencecityOctober 28, 2019 Read More
Publications of the Week A Rapid Triage Test for Active Pulmonary Tuberculosis in Adult Patients with Persistent CoughAhmad, R., et al. | October 28, 2019Tuberculosis remains a global health burden. Ahmad et al. used machine learning to develop an algorithm…sciencecityOctober 28, 2019 Read More
Publications of the Week Cell Swelling, Softening and Invasion in a Three-Dimensional Breast Cancer ModelHan, Y., H., et al. | October 24, 2019Control of the structure and function of three-dimensional multicellular tissues depends critically on the spatial…sciencecityOctober 24, 2019 Read More
Publications of the Week Unique Structural Features in an Nramp Metal Transporter Impart Substrate-Specific Proton Cotransport and a Kinetic Bias to Favor ImportBozzi, A., T., et al. | October 21, 2019Natural resistance-associated macrophage protein (Nramp) transporters enable uptake of essential transition metal micronutrients in numerous…sciencecityOctober 21, 2019 Read More
Publications of the Week Optical Pooled Screens in Human CellsFeldman, D., et al. | October 18, 2019Genetic screens are critical for the systematic identification of genes underlying cellular phenotypes. Pooling gene…sciencecityOctober 18, 2019 Read More
Publications of the Week Bacterial Variability in the Mammalian Gut Captured by a Single-Cell Synthetic OscillatorRiglar, D., T., et al. | October 15, 2019Synthetic gene oscillators have the potential to control timed functions and periodic gene expression in…sciencecityOctober 15, 2019 Read More
Publications of the Week Structural Basis for the Docking of mTORC1 on the Lysosomal SurfaceRogala, K.,B., et al. | October 14, 2019The mTORC1 protein kinase regulates growth in response to nutrients and growth factors. Nutrients promote…sciencecityOctober 14, 2019 Read More
Publications of the Week A Luminal Unfolding Microneedle Injector for Oral Delivery of MacromoleculesSalvador, E., C., et al. | October 11, 2019We developed an ingestible system capable of applying small micro-needle patches in the small intestine…sciencecityOctober 11, 2019 Read More