Publications of the Week The FUS::DDIT3 Fusion Oncoprotein Inhibits BAF Complex Targeting and Activity in Myxoid Liposarcoma Zullow, H., et al. | May 4, 2022 The Kadoch Lab is centered in understanding chromatin and gene regulatory mechanisms that underlie human…pthomsonMay 4, 2022 Read More
Publications of the Week Central Memory T Cells Are the Most Effective Precursors of Resident Memory T Cells in Human Skin Matos, T. R., et al. | April 30, 2022 Skin resident memory T cells (TRM) are important mediators of frontline immunity in response to…pthomsonApril 30, 2022 Read More
Publications of the Week Non-cleavable Hinge Enhances Avidity and Expansion of CAR-T Cells for Acute Myeloid Leukemia Leick, M. B., et al. | April 28, 2022 Chimeric antigen receptor (CAR) T cell therapy is effective in lymphoid malignancies, but there has been limited…pthomsonApril 28, 2022 Read More
Publications of the Week Genome-Wide Pleiotropy Analysis of Coronary Artery Disease and Pneumonia Identifies Shared Immune Pathways Yu, Z., et al. | April 22, 2022 Coronary artery disease (CAD) remains the leading cause of death despite scientific advances. Elucidating shared…pthomsonApril 22, 2022 Read More
Publications of the Week ADAR1 and Its Implications in Cancer Development and Treatment Baker, A., et al. | April 19, 2022 The epitranscriptome represents an emerging novel layer of gene regulation that goes awry in cancer.…pthomsonApril 19, 2022 Read More
Publications of the Week Genome-Wide Analysis of Somatic Noncoding Mutation Patterns in Cancer Dietlein, F., et al. | April 13, 2022 Numerous large-scale efforts have been undertaken to catalog and understand the biology of cancer-associated mutations…pthomsonApril 13, 2022 Read More
Publications of the Week Preclinical Modeling of Leiomyosarcoma Identifies Susceptibility to Transcriptional CDK Inhibitors through Antagonism of E2F-Driven Oncogenic Gene Expression Hemming, M. L., et al. | April 12, 2022 Leiomyosarcoma (LMS) is a neoplasm characterized by smooth muscle differentiation, complex copy-number alterations, tumor suppressor…pthomsonApril 12, 2022 Read More
Publications of the Week Types and Functions of Heterogeneity in Mycobacteria Chung, E. S., et al. | April 8, 2022 The remarkable ability of Mycobacterium tuberculosis to survive attacks from the host immune response and drug treatment…pthomsonApril 8, 2022 Read More
Publications of the Week Stitchr: Stitching Coding TCR Nucleotide Sequences from V/J/CDR3 Information Heather, J. M., et al. | April 5, 2022 The study and manipulation of T cell receptors (TCRs) is central to multiple fields across…pthomsonApril 5, 2022 Read More
Publications of the Week Orthogonally Induced Differentiation of Stem Cells for the Programmatic Patterning of Vascularized Organoids and Bioprinted Tissues Sylar-Scott, M. A., et al. | April 1, 2022 The generation of organoids and tissues with programmable cellular complexity, architecture and function would benefit…pthomsonApril 1, 2022 Read More