Publications of the Week Dynamic BH3 Profiling Identifies Pro-Apoptotic Drug Combinations for the Treatment of Malignant Pleural Mesothelioma Potter, D. S., et al. | May 24, 2023 Malignant pleural mesothelioma (MPM) has relatively ineffective first/second-line therapy for advanced disease and only 18%…pthomsonMay 24, 2023 Read More
Publications of the Week Atrophy in Behavioral Variant Frontotemporal Dementia Spans Multiple Large-Scale Prefrontal and Temporal Networks Eldaief, M. C., et al. | May 19, 2023 The identification of a neurodegenerative disorder’s distributed pattern of atrophy—or atrophy “signature”— can lend insights…pthomsonMay 19, 2023 Read More
Publications of the Week ERα-Associated Translocations Underlie Oncogene Amplifications in Breast Cancer Lee, J., et al. | May 18, 2023 Focal copy-number amplification is an oncogenic event. Although recent studies have revealed the complex structure1,2,3 and…pthomsonMay 18, 2023 Read More
Publications of the Week Autologous Neutralizing Antibodies Increase with Early Antiretroviral Therapy and Shape HIV Rebound after Treatment Interruption Esmaeilzadeh, E., et al. | May 12, 2023 Early initiation of antiretroviral therapy (ART) alters viral rebound kinetics after analytic treatment interruption (ATI)…pthomsonMay 12, 2023 Read More
Publications of the Week Abundant Aβ Fibrils in Ultracentrifugal Supernatants of Aqueous Extracts from Alzheimer’s Disease Brains Stern, A. M., et al. | May 11, 2023 Soluble oligomers of amyloid β-protein (Aβ) have been defined as aggregates in supernatants following ultracentrifugation…pthomsonMay 11, 2023 Read More
Publications of the Week Trehalose-Guanosine Glycopolymer Hydrogels Direct Adaptive Glia Responses in CNS Injury DuBois, E. M., et al. | May 5, 2023 Neural tissue damaged after central nervous system (CNS) injury does not naturally regenerate but is…pthomsonMay 5, 2023 Read More
Publications of the Week Dynamic Changes in Heparan Sulfate Nanostructure in Human Pluripotent Stem Cell Differentiation Al Mahbuba, D., et al. | May 2, 2023 The Kiessling Group uses chemical biology to elucidate the biological roles of carbohydrates, with a…pthomsonMay 2, 2023 Read More
Publications of the Week Cross-Modal Autoencoder Framework Learns Holistic Representations of Cardiovascular State Radhakrishnan, A., et al. | April 28, 2023 A fundamental challenge in diagnostics is integrating multiple modalities to develop a joint characterization of…pthomsonApril 28, 2023 Read More
Publications of the Week Mini-PCDH15 Gene Therapy Rescues Hearing in a Mouse Model of Usher Syndrome Type 1F Ivanchenko, M., et al. | April 28, 2023 Usher syndrome type 1 F (USH1F), caused by mutations in the protocadherin-15 gene (PCDH15), is characterized…pthomsonApril 28, 2023 Read More
Publications of the Week The Relaxin Receptor RXFP1 Signals Through a Mechanism of Autoinhibition Erlandson, S. C., et al. | April 21, 2023 The relaxin family peptide receptor 1 (RXFP1) is the receptor for relaxin-2, an important regulator…pthomsonApril 21, 2023 Read More