Publications of the Week Generation of Functionally Distinct T Cell Populations by Altering the Viscoelasticity of Their Extracellular Matrix Adu-Berchie, K., et al. | June 28, 2023 The efficacy of adoptive T cell therapies largely depends on the generation of T cell…pthomsonJune 28, 2023 Read More
Publications of the Week Optimal Dose of Cryoprecipitate in Massive Transfusion Following Trauma Dorken-Gallastegi, A., et al. | June 22, 2023 While cryoprecipitate is commonly included in massive transfusion protocols for hemorrhagic shock, the optimal dose of cryoprecipitate (Cryo) transfusion remains unknown.…pthomsonJune 22, 2023 Read More
Publications of the Week Directed Differentiation of Mouse Pluripotent Stem Cells into Functional Lung-Specific Mesenchyme Alber, A.B., et al. | June 19, 2023 While the generation of many lineages from pluripotent stem cells has resulted in basic discoveries…pthomsonJune 19, 2023 Read More
Publications of the Week Longitudinal Single-Cell Imaging of Engineered Strains with Stimulated Raman Scattering to Characterize Heterogeneity in Fatty Acid Production Tague, N., et al. | June 16, 2023 Understanding metabolic heterogeneity is critical for optimizing microbial production of valuable chemicals, but requires tools…pthomsonJune 16, 2023 Read More
Publications of the Week Thyroid Cancers Exhibit Oncogene-Enhanced Macropinocytosis That Is Restrained by IGF1R and Promotes Albumin-Drug-Conjugate Response Hu, H., et al. | June 14, 2023 Oncogene-driven macropinocytosis fuels nutrient scavenging in some cancer types, yet whether this occurs in thyroid…pthomsonJune 14, 2023 Read More
Publications of the Week Epigenetic Suppression of PGC1α (PPARGC1A) Causes Collateral Sensitivity to HMGCR-Inhibitors Within BRAF-Treatment Resistant Melanomas Liang, J., et al. | June 8, 2023 While targeted treatment against BRAF(V600E) improve survival for melanoma patients, many will see their cancer…pthomsonJune 8, 2023 Read More
Publications of the Week Distinct Longevity Mechanisms Across and Within Species and Their Association with Aging Tyshkovskiy, A., et al. | June 8, 2023 Lifespan varies within and across species, but the general principles of its control remain unclear.…pthomsonJune 8, 2023 Read More
Publications of the Week Irisin Acts through Its Integrin Receptor in a Two-Step Process Involving Extracellular Hsp90α A, M., et al. | June 2, 2023 Exercise benefits the human body in many ways. Irisin is secreted by muscle, increased with…pthomsonJune 2, 2023 Read More
Publications of the Week HLA Class I Signal Peptide Polymorphism Determines the Level of CD94/NKG2–HLA-E-Mediated Regulation of Effector Cell Responses Lin, Z., et al. | June 2, 2023 Human leukocyte antigen (HLA)-E binds epitopes derived from HLA-A, HLA-B, HLA-C and HLA-G signal peptides…pthomsonJune 2, 2023 Read More
Publications of the Week Protective Renalase-Deficiency in Beta Cells Shapes Immune Metabolism and Function in Autoimmune Diabetes Bode, K., et al. | May 25, 2023 Type 1 diabetes (T1D) is caused by the immune-mediated loss of pancreatic beta cells that…pthomsonMay 25, 2023 Read More