Publications of the Week Mucin O-Glycans Suppress Quorum-Sensing Pathways and Genetic Transformation in Streptococcus MutansWerlang, C. A., et al. | March 26, 2021Mucus barriers accommodate trillions of microorganisms throughout the human body while preventing pathogenic colonization. In…pthomsonMarch 26, 2021 Read More
Publications of the Week Checkpoint Blockade Toxicities: Insights into Autoimmunity and TreatmentWalsh, M. J. and Dougan, M. | March 23, 2021Checkpoint blockade has transformed not only the way cancers are treated, but also highlighted the…pthomsonMarch 23, 2021 Read More
Publications of the Week Interleukin-6 Produced by Enteric Neurons Regulates the Number and Phenotype of Microbe-Responsive Regulatory T Cells in the GutYan, Y., et al. | March 19, 2021The immune and enteric nervous (ENS) systems monitor the frontier with commensal and pathogenic microbes…pthomsonMarch 19, 2021 Read More
Publications of the Week Barcoded Oligonucleotides Ligated on RNA Amplified for Multiplexed and Parallel in Situ AnalysesLiu, S., et al. | March 16, 2021We present barcoded oligonucleotides ligated on RNA amplified for multiplexed and parallel insitu analyses (BOLORAMIS),…sciencecityMarch 16, 2021 Read More
Publications of the Week Cell Derived Extracellular Matrix-Rich Biomimetic Substrate Supports Podocyte Proliferation, Differentiation and Maintenance of Native PhenotypeSatyam, A., et al. | March 15, 2021Current technologies and available scaffold materials do not support long-term cell viability, differentiation and maintenance…sciencecityMarch 15, 2021 Read More
Publications of the Week Chemokine CCL5 Promotes Robust Optic Nerve Regeneration and Mediates Many of the Effects of CNTF Gene TherapyXie, L., et al. | March 11, 2021Ciliary neurotrophic factor (CNTF) is a leading therapeutic candidate for several ocular diseases and induces…sciencecityMarch 11, 2021 Read More
Publications of the Week Increased Stem Cell Proliferation in Atherosclerosis Accelerates Clonal HematopoiesisHeyde, A., et al. | March 10, 2021Clonal hematopoiesis, a condition in which individual hematopoietic stem cell clones generate a disproportionate fraction…sciencecityMarch 10, 2021 Read More
Publications of the Week Cryo-EM Structure of an Activated GPCR-G Protein Complex in Lipid NanodiscsZhang, M., et al. | March 5, 2021G-protein-coupled receptors (GPCRs) are the largest superfamily of transmembrane proteins and the targets of over…sciencecityMarch 5, 2021 Read More
Publications of the Week Clinical Implications of Colorectal Cancer Stem Cells in the Age of Single-Cell Omics and Targeted TherapiesFrank, M.H., et al. | March 2, 2021The cancer stem cell (CSC) concept emerged from the recognition of inherent tumor heterogeneity and…sciencecityMarch 2, 2021 Read More
Publications of the Week Elavl1 Impacts Osteogenic Differentiation and mRNA Levels of Genes Involved in ECM OrganizationKota, S. K., et al. | February 24, 2021Posttranscriptional gene regulation by Adenylate Uridylate (AU) rich element RNA binding protein, Elavl1 has been…sciencecityFebruary 24, 2021 Read More