Publications of the Week A Zpr1 Co-chaperone Mediates Folding of Eukaryotic Translation Elongation Factor 1A via a GTPase Cycle McQuown, A., et al. | August 24, 2023 General protein folding is mediated by chaperones that utilize ATP hydrolysis to regulate client binding…sciencecityAugust 24, 2023 Read More
Publications of the Week KDM6A Epigenetically Regulates Subtype Plasticity in Small Cell Lung Cancer Duplaquet, L., et al. | August 22, 2023 Small cell lung cancer (SCLC) exists broadly in four molecular subtypes: ASCL1, NEUROD1, POU2F3 and…pthomsonAugust 22, 2023 Read More
Publications of the Week Three Studies Highlight How Proteins Are Altered in Multiple Cancer Types Geffen, Y., et al. | August 16, 2023 Over the past two decades, scientists have shed light on the genetic mutations that drive…pthomsonAugust 16, 2023 Read More
Publications of the Week Delayed and Attenuated Antibody Responses to Coronavirus Disease 2019 Vaccination with Poor Cross-Variant Neutralization in Solid-Organ Transplant Recipients—A Prospective Longitudinal Study Liew, M.Y., et al. | August 15, 2023 Therapeutically immunosuppressed transplant recipients exhibit attenuated responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)…pthomsonAugust 15, 2023 Read More
Publications of the Week Tissue Perfusion Pressure Enables Continuous Hemodynamic Evaluation and Risk Prediction in the Intensive Care Unit Chandrasekhar, A., et al. | August 11, 2023 Treatment of circulatory shock in critically ill patients requires management of blood pressure using invasive…pthomsonAugust 11, 2023 Read More
Publications of the Week Exposure of iPSC-Derived Human Microglia to Brain Substrates Enables the Generation and Manipulation of Diverse Transcriptional States In Vitro Dolan, M., et al. | August 10, 2023 Microglia, the macrophages of the brain parenchyma, are key players in neurodegenerative diseases such as…pthomsonAugust 10, 2023 Read More
Publications of the Week Exploring the Relationship Between History of Infertility and the Experience of Menopausal Symptoms Fitz, V.W., et al. | August 4, 2023 The aim of the study is to examine longitudinal associations of history of infertility with menopausal symptoms…pthomsonAugust 4, 2023 Read More
Publications of the Week A Spatiotemporal Notch Interaction Map from Plasma Membrane to Nucleus Martin, A.P., et al. | August 4, 2023 Notch signaling relies on ligand-induced proteolysis of the transmembrane receptor Notch to liberate a nuclear…pthomsonAugust 4, 2023 Read More
Publications of the Week NLRP11 Is a Pattern Recognition Receptor for Bacterial Lipopolysaccharide in the Cytosol of Human Macrophages Rojas-Lopez, M.,et al. | July 28, 2023 Endotoxin—bacterial lipopolysaccharide (LPS)—is a driver of lethal infection sepsis through excessive activation of innate immune…pthomsonJuly 28, 2023 Read More
Publications of the Week Modeling Epigenetic Lesions That Cause Gliomas Rahme, G.J., et al. | July 27, 2023 Epigenetic lesions that disrupt regulatory elements represent potential cancer drivers. However, we lack experimental models…pthomsonJuly 27, 2023 Read More