Publications of the Week Allelic Chromatin Structure Precedes Imprinted Expression of Kcnk9 During Neurogenesis Loftus, D., et al. | October 23, 2023 Differences in chromatin state inherited from the parental gametes influence the regulation of maternal and…sciencecityOctober 23, 2023 Read More
Publications of the Week A Mouse Model with High Clonal Barcode Diversity for Joint Lineage, Transcriptomic, and Epigenomic Profiling in Single Cells Li, L., et al. | October 20, 2023 Cellular lineage histories and their molecular states encode fundamental principles of tissue development and homeostasis.…sciencecityOctober 20, 2023 Read More
Publications of the Week A Disordered Region Controls cBAF Activity via Condensation and Partner Recruitment Patil, A., et al. | October 18, 2023 Intrinsically disordered regions (IDRs) represent a large percentage of overall nuclear protein content. The prevailing…sciencecityOctober 18, 2023 Read More
Publications of the Week Targeting PGLYRP1 Promotes Antitumor Immunity While Inhibiting Autoimmune Neuroinflammation Schnell, A., et al. | October 16, 2023 Co-inhibitory and checkpoint molecules suppress T cell function in the tumor microenvironment, thereby rendering T…sciencecityOctober 16, 2023 Read More
Publications of the Week Cell-Type-Specific Regulation of APOE and CLU Levels in Human Neurons by the Alzheimer’s Disease Risk Gene SORL1 Lee, H., et al. | October 13, 2023 SORL1 is implicated in the pathogenesis of Alzheimer’s disease (AD) through genetic studies. To interrogate…sciencecityOctober 13, 2023 Read More
Publications of the Week Atypical Droplet Digital Polymerase Chain Reaction Patterns That Indicate Uncommon but Clinically Actionable EGFR Mutations in Lung Cancer Lechner, A., et al. | October 11, 2023 Droplet digital polymerase chain reaction (ddPCR) is a sensitive method to detect common pathogenic EGFR…sciencecityOctober 11, 2023 Read More
Publications of the Week Spatially Aware Deep Learning Reveals Tumor Heterogeneity Patterns That Encode Distinct Kidney Cancer States Nyman, J., et al. | October 9, 2023 Clear cell renal cell carcinoma (ccRCC) is molecularly heterogeneous, immune infiltrated, and selectively sensitive to…sciencecityOctober 9, 2023 Read More
Publications of the Week Assessment and Validation of Enrichment and Target Capture Approaches to Improve Mycobacterium tuberculosis WGS from Direct Patient Samples Mann, B., et al. | October 6, 2023 Within-host Mycobacterium tuberculosis (Mtb) diversity may detect antibiotic resistance or predict tuberculosis treatment failure and is…sciencecityOctober 6, 2023 Read More
Publications of the Week Automated Segmentation of Sacral Chordoma and Surrounding Muscles Using Deep Learning Ensemble Boussioux, L., et al. | October 4, 2023 The manual segmentation of organ structures in radiation oncology treatment planning is a time-consuming and…sciencecityOctober 4, 2023 Read More
Publications of the Week A Foundational Approach to Culture and Analyze Malnourished Organoids Perlman, M., et al. | October 2, 2023 The gastrointestinal (GI) epithelium plays a major role in nutrient absorption, barrier formation, and innate…sciencecityOctober 2, 2023 Read More