Publications of the Week HDAC6 Mediates an Aggresome-Like Mechanism for NLRP3 and Pyrin Inflammasome Activation Magupalli, V.G., et al. | September 28, 2020 Canonical inflammasomes are multicomponent protein complexes that play key roles in immune surveillance of infections…eabramovichSeptember 28, 2020 Read More
Publications of the Week A Regulatory T Cell Notch4–GDF15 Axis Licenses Tissue Inflammation in Asthma Harb, H., et al. | September 24, 2020 This study provides a comprehensive framework for understanding inflammation in asthma. The authors identified a…eabramovichSeptember 24, 2020 Read More
Publications of the Week Antibiotic Susceptibility Signatures Identify Potential Antimicrobial Targets in the Acinetobacter baumannii Cell Envelope Geisinger, E., et al. | September 23, 2020 A unique, protective cell envelope contributes to the broad drug resistance of the nosocomial pathogen Acinetobacter…eabramovichSeptember 23, 2020 Read More
Publications of the Week CSF1R Inhibition by a Small-Molecule Inhibitor Is Not Microglia Specific; Affecting Hematopoiesis and the Function of Macrophages Lei, F., et al. | September 16, 2020 Colony-stimulating factor 1 receptor (CSF1R) inhibition has been extensively adopted by many laboratories for the…eabramovichSeptember 16, 2020 Read More
Publications of the Week Cell-Based Artificial APC Resistant to Lentiviral Transduction for Efficient Generation of CAR-T Cells from Various Cell Sources Schmidts, A., et al. | September 14, 2020 Adoptive cell therapy with chimeric antigen receptor T cells (CAR-T) has become a standard treatment…eabramovichSeptember 14, 2020 Read More
Publications of the Week STING Cyclic Dinucleotide Sensing Originated in Bacteria Morehouse, B.R., et al. | September 11, 2020 Stimulator of interferon genes (STING) is a receptor in human cells that senses foreign cyclic…eabramovichSeptember 11, 2020 Read More
Publications of the Week Ultra-Sensitive Serial Profiling of SARS-CoV-2 Antigens and Antibodies in Plasma to Understand Disease Progression in COVID-19 Patients with Severe Disease Ogata, A.F., et al. | September 9, 2020 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over 21 million people worldwide since…eabramovichSeptember 9, 2020 Read More
Publications of the Week Functionally Uncoupled Transcription–Translation in Bacillus subtilis Johnson, G.E., et al. | September 7, 2020 Transcription-translation coupling has long been considered a defining feature of the central dogma in bacteria.…eabramovichSeptember 7, 2020 Read More
Publications of the Week A Single Human VH-gene Allows for a Broad-Spectrum Antibody Response Targeting Bacterial Lipopolysaccharides in the Blood Sangesland, M., et al. | September 4, 2020 B cell receptors (BCRs) display a combination of variable (V)-gene-encoded complementarity determining regions (CDRs) and…eabramovichSeptember 4, 2020 Read More
Publications of the Week Enhancer Dependence of Cell-Type–Specific Gene Expression Increases with Developmental Age Cai, W., et al. | September 2, 2020 Gene regulatory logic reflects the occupancy of cis elements by transcription factors and the configuration of promoters…eabramovichSeptember 2, 2020 Read More