Publications of the Week Hair-Bearing Human Skin Generated Entirely from Pluripotent Stem Cells Lee, J., et al. | June 5, 2020 The skin is a multilayered organ, equipped with appendages (that is, follicles and glands), that…eabramovichJune 5, 2020 Read More
Publications of the Week Loss of Heterozygosity of Essential Genes Represents a Widespread Class of Potential Cancer Vulnerabilities Nichols, C.A., et al. | June 1, 2020 About one out of every six genes loses one of its two alleles in the…eabramovichJune 1, 2020 Read More
Publications of the Week Transcriptional and Cellular Diversity of the Human Heart Tucker, N.R., et al. | May 28, 2020 The human heart requires a complex ensemble of specialized cell types to perform its essential…eabramovichMay 28, 2020 Read More
Publications of the Week Patient hiPSCs Identify Vascular Smooth Muscle Arylacetamide Deacetylase as Protective against Atherosclerosis Toyohara, T., et al. | May 25, 2020 Although susceptibility to cardiovascular disease (CVD) is different for every patient, why some patients with…eabramovichMay 25, 2020 Read More
Publications of the Week An Engineered CRISPR-Cas9 Mouse Line for Simultaneous Readout of Lineage Histories and Gene Expression Profiles in Single Cells Bowling, S., et al. | May 22, 2020 Tracing the lineage history of cells is key to answering diverse and fundamental questions in…eabramovichMay 22, 2020 Read More
Publications of the Week Facultative Protein Selenation Regulates Redox Sensitivity, Adipose Tissue Thermogenesis, and Obesity Jedrychowski, M.P., et al. | May 18, 2020 Oxidation of cysteines by reactive oxygen species (ROS) initiates thermogenesis in brown and beige adipose…eabramovichMay 18, 2020 Read More
Publications of the Week Increased Mitochondrial Calcium Levels Associated with Neuronal Death in a Mouse Model of Alzheimer’s Disease Calvo-Rodriguez, M., et al. | May 14, 2020 This work addresses the toxic effects of the protein amyloid on the mitochondrial calcium homeostasis…eabramovichMay 14, 2020 Read More
Publications of the Week Proteomic and Biological Profiling of Extracellular Vesicles from Alzheimer’s Disease Human Brain Tissues Muraoka, S., et al. | May 12, 2020 This publication is the first comprehensive quantitative proteomics study of extracellular vesicles (EV) isolated from…eabramovichMay 12, 2020 Read More
Publications of the Week Factors Promoting Nuclear Envelope Assembly Independent of the Canonical ESCRT Pathway Lee, I., et al. | May 7, 2020 The nuclear envelope (NE) undergoes dynamic remodeling to maintain NE integrity, a process involving the…eabramovichMay 7, 2020 Read More
Publications of the Week Disease-Associated Astrocytes in Alzheimer’s Disease and Aging Habib, N., et al. | May 5, 2020 The role of non-neuronal cells in Alzheimer’s disease progression has not been fully elucidated. Using…eabramovichMay 5, 2020 Read More