Publications of the Week Elavl1 Impacts Osteogenic Differentiation and mRNA Levels of Genes Involved in ECM Organization Kota, S. K., et al. | February 24, 2021 Posttranscriptional gene regulation by Adenylate Uridylate (AU) rich element RNA binding protein, Elavl1 has been…sciencecityFebruary 24, 2021 Read More
Publications of the Week Two Macrophages, Osteoclasts and Microglia: From Development to Pleiotropy Lee, J., et al. | February 23, 2021 Tissue-resident macrophages are highly specialized to their tissue-specific microenvironments, activated by various inflammatory signals and…sciencecityFebruary 23, 2021 Read More
Publications of the Week Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine Baden, L. R., et al. | February 18, 2021 Vaccines are needed to prevent coronavirus disease 2019 (Covid-19) and to protect persons who are…sciencecityFebruary 18, 2021 Read More
Publications of the Week Toward Robust Mammography-Based Models for Breast Cancer Risk Yala, A., et al. | February 18, 2021 We are developing algorithms that can learn from rich and widely collected medical data, like…sciencecityFebruary 18, 2021 Read More
Publications of the Week Discrete SARS-CoV-2 Antibody Titers Track with Functional Humoral Stability Bartsch, Y., et al. | February 17, 2021 Antibodies serve as biomarkers of infection, but if sustained can confer long-term immunity. Yet, for…sciencecityFebruary 17, 2021 Read More
Publications of the Week Regulatory Genomic Circuitry of Human Disease Loci by Integrative Epigenomics Boix, C., et al. | February 10, 2021 Annotating the molecular basis of human disease remains an unsolved challenge, as 93% of disease…sciencecityFebruary 10, 2021 Read More
Publications of the Week Tripartite Motif 22 (TRIM22) Protein Restricts Herpes Simplex Virus 1 by Epigenetic Silencing of Viral Immediate-Early Genes Reddi, T., et al. | February 9, 2021 The Knipe laboratory studies the mechanisms by which herpes simplex virus (HSV) undergoes a productive…emcguinnFebruary 9, 2021 Read More
Publications of the Week Opposing Immune and Genetic Mechanisms Shape Oncogenic Programs in Synovial Sarcoma Jerbyn-Arnon, L., et al. | February 5, 2021 Synovial sarcoma (SyS) is an aggressive neoplasm driven by the SS18–SSX fusion, and is characterized…emcguinnFebruary 5, 2021 Read More
Publications of the Week Targeting a BRAF/MAPK Pathway Rescues Podocyte Lipid Peroxidation in CoQ Deficiency Kidney Disease Sidhom, E., et al. | February 1, 2021 Mutations affecting mitochondrial coenzyme Q (CoQ) biosynthesis lead to kidney failure due to selective loss…emcguinnFebruary 1, 2021 Read More
Publications of the Week Cryo-EM Structure of the B Cell Co-Receptor CD19 Bound to the Tetraspanin CD81 Susa, K., et al. | January 28, 2021 Signaling through the CD19-CD81 co-receptor complex, in combination with the B cell receptor, is a…emcguinnJanuary 28, 2021 Read More