Publications of the Week Systematic Quantitative Analysis of Ribosome Inventory During Nutrient Stress An, H., et al. | July 17, 2020 Mammalian cells reorganize their proteomes in response to nutrient stress through translational suppression and degradative…eabramovichJuly 17, 2020 Read More
Publications of the Week The Evolutionarily Conserved piRNA-Producing Locus pi6 Is Required for Male Mouse Fertility Wu, PH., et al. | July 14, 2020 The results suggest that in mammals — including human beings — a convoluted network of…eabramovichJuly 14, 2020 Read More
Publications of the Week An Ecological Framework to Understand the Efficacy of Fecal Microbiota Transplantation Xiao, Y., et al. | July 10, 2020 The authors present an ecological framework to understand the efficacy of fecal microbiota transplantation (FMT)…eabramovichJuly 10, 2020 Read More
Publications of the Week Sex Differences in Gene Expression and Regulatory Networks across 29 Human Tissues Lopes-Ramos, C.M., et al. | July 7, 2020 The authors modeled the network of factors that control gene expression and observed that these…eabramovichJuly 7, 2020 Read More
Publications of the Week Tau Molecular Diversity Contributes to Clinical Heterogeneity in Alzheimer’s Disease Dujardin, S., et al. | July 3, 2020 Alzheimer’s disease (AD) causes unrelenting, progressive cognitive impairments, but its course is heterogeneous, with a…eabramovichJuly 3, 2020 Read More
Publications of the Week The Role of Bone Morphogenetic Protein Signaling in Non-Alcoholic Fatty Liver Disease Thayer, T.E., et al. | July 2, 2020 Despite the growing burden and high morbidity and mortality associated with non-alcoholic fatty liver disease…eabramovichJuly 2, 2020 Read More
Publications of the Week Drug GRADE: An Integrated Analysis of Population Growth and Cell Death Reveals Drug-Specific and Cancer Subtype-Specific Response Profiles Schwartz, H.R., et al. | June 29, 2020 The typical measurement for evaluating drugs doesn’t distinguish between responses that are due to inhibition…eabramovichJune 29, 2020 Read More
Publications of the Week cGMP via PKG Activates 26S Proteasomes and Enhances Degradation of Proteins, Including Ones that Cause Neurodegenerative Diseases VerPlank, J.J.S., et al. | June 26, 2020 The authors demonstrate that agents that raise cGMP and activate the cGMP-dependent protein kinase (PKG),…eabramovichJune 26, 2020 Read More
Publications of the Week Inhibition of the Translesion Synthesis Polymerase REV1 Exploits Replication Gaps as a Cancer Vulnerability Nayak, S., et al. | June 22, 2020 The authors reveal how a well described anti-cancer barrier, “the replication stress response,” is overcome…eabramovichJune 22, 2020 Read More
Publications of the Week Keap1 Mutation Renders Lung Adenocarcinomas Dependent on Slc33a1 Romero, R., et al. | June 19, 2020 Approximately 20–30% of human lung adenocarcinomas (LUADs) harbor mutations in Kelch-like ECH-associated protein 1 (KEAP1)…eabramovichJune 19, 2020 Read More