Publications of the Week A Regulatory T Cell Notch4–GDF15 Axis Licenses Tissue Inflammation in AsthmaHarb, H., et al. | September 24, 2020This study provides a comprehensive framework for understanding inflammation in asthma. The authors identified a…eabramovichSeptember 24, 2020 Read More
Publications of the Week Antibiotic Susceptibility Signatures Identify Potential Antimicrobial Targets in the Acinetobacter baumannii Cell EnvelopeGeisinger, E., et al. | September 23, 2020A unique, protective cell envelope contributes to the broad drug resistance of the nosocomial pathogen Acinetobacter…eabramovichSeptember 23, 2020 Read More
Publications of the Week CSF1R Inhibition by a Small-Molecule Inhibitor Is Not Microglia Specific; Affecting Hematopoiesis and the Function of MacrophagesLei, F., et al. | September 16, 2020Colony-stimulating factor 1 receptor (CSF1R) inhibition has been extensively adopted by many laboratories for the…eabramovichSeptember 16, 2020 Read More
Publications of the Week Cell-Based Artificial APC Resistant to Lentiviral Transduction for Efficient Generation of CAR-T Cells from Various Cell SourcesSchmidts, A., et al. | September 14, 2020Adoptive cell therapy with chimeric antigen receptor T cells (CAR-T) has become a standard treatment…eabramovichSeptember 14, 2020 Read More
Publications of the Week STING Cyclic Dinucleotide Sensing Originated in BacteriaMorehouse, B.R., et al. | September 11, 2020Stimulator of interferon genes (STING) is a receptor in human cells that senses foreign cyclic…eabramovichSeptember 11, 2020 Read More
Publications of the Week Ultra-Sensitive Serial Profiling of SARS-CoV-2 Antigens and Antibodies in Plasma to Understand Disease Progression in COVID-19 Patients with Severe DiseaseOgata, A.F., et al. | September 9, 2020Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over 21 million people worldwide since…eabramovichSeptember 9, 2020 Read More
Publications of the Week Functionally Uncoupled Transcription–Translation in Bacillus subtilisJohnson, G.E., et al. | September 7, 2020Transcription-translation coupling has long been considered a defining feature of the central dogma in bacteria.…eabramovichSeptember 7, 2020 Read More
Publications of the Week A Single Human VH-gene Allows for a Broad-Spectrum Antibody Response Targeting Bacterial Lipopolysaccharides in the BloodSangesland, M., et al. | September 4, 2020B cell receptors (BCRs) display a combination of variable (V)-gene-encoded complementarity determining regions (CDRs) and…eabramovichSeptember 4, 2020 Read More
Publications of the Week Enhancer Dependence of Cell-Type–Specific Gene Expression Increases with Developmental AgeCai, W., et al. | September 2, 2020Gene regulatory logic reflects the occupancy of cis elements by transcription factors and the configuration of promoters…eabramovichSeptember 2, 2020 Read More
Publications of the Week Engineering Designer Beta Cells with a CRISPR-Cas9 Conjugation PlatformLim, D., et al. | August 28, 2020The authors developed a convenient platform to conjugate molecules to Cas9, and using this platform…eabramovichAugust 28, 2020 Read More