Publications of the Week The Evolutionary Plasticity of Chromosome Metabolism Allows Adaptation to Constitutive DNA Replication Stress Fumasoni, M. et al. | April 8, 2020 Many biological features are conserved and thus considered to be resistant to evolutionary change. While…sciencecityApril 8, 2020 Read More
Publications of the Week Nociceptive Neurons Respond to Multimodal Stimuli in Manduca Sexta Caron, D., P., et al. | April 3, 2020 The caterpillar Manduca sexta produces a highly stereotyped strike behavior in response to noxious thermal or mechanical…sciencecityApril 3, 2020 Read More
Publications of the Week Heart-on-a-Chip Model with Integrated Extra- and Intracellular Bioelectronics for Monitoring Cardiac Electrophysiology under Acute Hypoxia Liu, H., et al | April 1, 2020 We demonstrated a bioelectronic heart-on-a-chip model for studying the effects of acute hypoxia on cardiac…sciencecityApril 1, 2020 Read More
Publications of the Week FGF6 and FGF9 Regulate UCP1 Expression Independent of Brown Adipogenesis Shamsi, F., et al. | March 26, 2020 Uncoupling protein-1 (UCP1) plays a central role in energy dissipation in brown adipose tissue (BAT).…sciencecityMarch 26, 2020 Read More
Publications of the Week Native Zinc Catalyzes Selective and Traceless Release of Small Molecules in β-Cells Lee, M., et al. | March 24, 2020 The loss of insulin-producing β-cells is the central pathological event in type 1 and 2…sciencecityMarch 24, 2020 Read More
Publications of the Week Molecular Basis for Catabolism of the Abundant Metabolite Trans-4-Hydroxy-L-Proline by a Microbial Glycyl Radical Enzyme Backman, L., R., F., et al. | March 19, 2020 The glycyl radical enzyme (GRE) superfamily utilizes a glycyl radical cofactor to catalyze difficult chemical…sciencecityMarch 19, 2020 Read More
Publications of the Week Evolutionary Repair: Changes in Multiple Functional Modules Allow Meiotic Cohesin to Support Mitosis Hsieh, Y., P., et al. | March 13, 2020 The role of proteins often changes during evolution, but we do not know how cells…sciencecityMarch 13, 2020 Read More
Publications of the Week Microglial Depletion Disrupts Normal Functional Development of Adult-Born Neurons in the Olfactory Bulb Wallace, J., et al. | March 12, 2020 Microglia play key roles in regulating synapse development and refinement in the developing brain, but…sciencecityMarch 12, 2020 Read More
Publications of the Week Cytochrome P450 Oxidoreductase Contributes to Phospholipid Peroxidation in Ferroptosis Zou, Y., et al. | March 5, 2020 Ferroptosis is widely involved in degenerative diseases in various tissues including kidney, liver and brain,…sciencecityMarch 5, 2020 Read More
Publications of the Week Development of an Autonomous and Bifunctional Quorum-Sensing Circuit for Metabolic Flux Control in Engineered Escherichia coli Christina V. Dinh and Kristala L. J. Prather | March 2, 2020 Efficient microbial synthesis in challenging pathways relies on dynamic regulation of multiple metabolic fluxes to…sciencecityMarch 2, 2020 Read More