Publications of the Week

Subtle changes in gene expression direct cells to distinct cellular states. Identifying and controlling dose-dependent…

Astrocytes and microglia are emerging key regulators of activity-dependent synapse remodeling that engulf and remove…

Allogeneic cellular immunotherapy exhibits promising efficacy for cancer treatment, but donor cell rejection remains a…

Inflammation is an essential defense response but operates at the cost of normal tissue functions.…

Prime editors make programmed genome modifications by writing new sequences into extensions of nicked DNA…

Acute leukemia requires precise molecular classification and urgent treatment. However, standard-of-care diagnostic tests are time-intensive…

Chimeric antigen receptor (CAR) T cells are highly effective in haematological malignancies1. However, progressive loss…

Prime editors make programmed genome modifications by writing new sequences into extensions of nicked DNA…

Loss-of-function variants in the lipid transporter ABCA7 substantially increase the risk of Alzheimer’s disease1,2, yet…

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive cognitive decline, yet its epigenetic…