Publications of the Week

Transcription reshapes DNA folding within living cells, driving patterns of gene expression. However, this process…

Targeted insertion of large DNA fragments has promising applications for genome engineering and gene therapy1,2.…

Chromatin dynamics control the timescales of essential biological processes and reflect how chromatin is organized…

Cancer-causing mutations have been identified primarily from positive selection signals in cancer genomes. However, positive…

Human cerebral organoids derived from induced pluripotent stem cells can recapture early developmental processes and…

Engineered virus-like particles (eVLPs) are promising vehicles for transient delivery of gene editing agents. While…

Cellular water content governs the concentration of all biomolecules inside a cell, thereby influencing the…

Despite the promise of engineered tissue implants for the treatment of organ failure, scaling of…

Immature neurons in the adult brain migrate into existing circuits, contributing to plasticity, learning, and…

Intestinal mucins have extended O-glycans comprised primarily of the common Core 1 O-glycan (Galβ1-3GalNAcα1-Ser/Thr/Tyr) and…