Publications of the Week The E3 Ubiquitin Ligase Mechanism Specifying Targeted microRNA Degradation Farnung, J., et al. | April 8, 2026 MicroRNAs (miRNAs) associate with Argonaute (AGO) proteins to form complexes that down-regulate target RNAs, including…karnottApril 8, 2026 Read More
Publications of the Week Cell Painting for Cytotoxicity and Mode-Of-Action Analysis in Primary Human Hepatocytes Ewald, J., et al. | April 1, 2026 Scalable, human-relevant approaches for detecting compound modes of action are needed to improve chemical safety…karnottApril 1, 2026 Read More
Publications of the Week Dopamine and Serotonin Inversely Modulate D2 Medium Spiny Neurons to Regulate Cocaine Reward Cardozo Pinto, D., et al. | March 30, 2026 Classic theories propose opponent functions for striatal dopamine (DA) and serotonin (5-hydroxytryptamine; 5HT), with DA…karnottMarch 30, 2026 Read More
Publications of the Week The E3 Ubiquitin Ligase Mechanism Specifying Targeted microRNA Degradation Farnung, J., et al. | March 26, 2026 MicroRNAs (miRNAs) associate with Argonaute (AGO) proteins to form complexes that down-regulate target RNAs, including…karnottMarch 26, 2026 Read More
Publications of the Week Multidimensional Profiling of Heterogeneity in Supratentorial Ependymomas Jeong, D., et al. | March 24, 2026 Supratentorial ependymomas are aggressive childhood brain cancers that retain features of neurodevelopmental cell types1 and…karnottMarch 24, 2026 Read More
Publications of the Week Leveraging Tissue-Resident Memory T Cells for Non-Invasive Immune Monitoring via Microneedle Skin Patches Jalili, S., et al. | March 17, 2026 Detecting antigen-specific lymphocytes is crucial for immune monitoring in vaccination, infection, cancer and autoimmunity. However,…karnottMarch 17, 2026 Read More
Publications of the Week Microbiota-Mediated Induction of Beige Adipocytes in Response to Dietary Cues Tanoue, T., et al. | March 12, 2026 Interactions between diet and the gut microbiota are fundamental to metabolic health, shaping energy balance…karnottMarch 12, 2026 Read More
Publications of the Week Bioresorbable RFID Capsule for Assessing Medication Adherence Say, M., et al. | March 9, 2026 Drs. Mehmet Girayhan Say, first author, and Giovanni Traverso, senior author. Swallow, Dissolve, Notify: MIT’s…karnottMarch 9, 2026 Read More
Publications of the Week miR126-Mediated Alteration of Vascular Integrity in Rett Syndrome Osaki, T., et al. | March 4, 2026 Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in methyl-CpG binding protein 2…karnottMarch 4, 2026 Read More
Publications of the Week Functional Dissection of Complex Trait Variants at Single-Nucleotide Resolution Siraj, L., et al. | March 2, 2026 Identifying the causal variants and mechanisms that drive complex traits and diseases remains a core…karnottMarch 2, 2026 Read More