Publications of the Week Alternative Start Codon Selection Shapes Mitochondrial Function and Rare Human Diseases Ly, J., et al. | December 11, 2025 Rare genetic diseases collectively affect millions of individuals. A common target of many rare diseases…karnottDecember 11, 2025 Read More
Publications of the Week Quantitative Cell Type–Specific Immunopeptidome Analysis of Macrophage and Tumor Coevolution Reveals Therapeutic MHC-I Peptides in Glioblastoma Cui, Y., et al. | December 8, 2025 Immune checkpoint inhibitors have shown impressive performance in treating several types of solid tumors. However,…karnottDecember 8, 2025 Read More
Publications of the Week Human Plasma Proteomic Profile of Clonal Hematopoiesis Yu, Z., et al. | December 4, 2025 Plasma proteomic profiles associated with subclinical somatic mutations in blood cells may offer insights into…karnottDecember 4, 2025 Read More
Publications of the Week A Stochastic RNA Editing Process Targets a Select Number of Sites in Individual Drosophila Glutamatergic Motoneurons Crane, A., et al. | December 1, 2025 RNA editing is a post-transcriptional source of protein diversity and occurs across the animal kingdom.…karnottDecember 1, 2025 Read More
Publications of the Week Intracellular Competition Shapes Plasmid Population Dynamics Rossine, F., et al. | November 28, 2025 From populations of multicellular organisms to selfish genetic elements, conflicts between levels of biological organization…karnottNovember 28, 2025 Read More
Publications of the Week A Transcriptomic Atlas of Astrocyte Heterogeneity Across Space and Time in Mouse and Marmoset Schroeder, M., et al. | November 27, 2025 How astrocyte regionalization unfolds over development is not fully understood. We used single-nucleus RNA sequencing…karnottNovember 27, 2025 Read More
Publications of the Week Prime Editing-Installed Suppressor tRNAs for Disease-Agnostic Genome Editing Pierce, S., et al. | November 21, 2025 Precise genome-editing technologies such as base editing1,2 and prime editing3 can correct most pathogenic gene…karnottNovember 21, 2025 Read More
Publications of the Week Immunopeptidomics Can Inform the Design of mRNA Vaccines for the Delivery of Mycobacterium tuberculosis MHC Class II Antigens Leddy, O., et al. | November 17, 2025 No currently licensed vaccine reliably prevents pulmonary tuberculosis (TB), a leading cause of infectious disease…karnottNovember 17, 2025 Read More
Publications of the Week Alternative Start Codon Selection Shapes Mitochondrial Function and Rare Human Diseases Ly, J., et al. | November 14, 2025 Rare genetic diseases collectively affect millions of individuals. A common target of many rare diseases…karnottNovember 14, 2025 Read More
Publications of the Week Degradable Cyclic Amino Alcohol Ionizable Lipids as Vectors for Potent Influenza mRNA Vaccines Rudra, A., et al. | November 13, 2025 The next generation of mRNA vaccines must address several limitations, including enhancing vaccine potency and…karnottNovember 13, 2025 Read More