Publications of the Week

Prime editing is a versatile clinical genome editing method that enables precise substitutions, small insertions…

Drug delivery to the oesophagus poses unique challenges, including rapid transit time due to gravity…

Enteric pathogens are a major contributor to the global disease burden, necessitating vaccines capable of…

Although the gut microbiome is implicated in colorectal cancer (CRC), microbiome and metabolome alterations along…

Sensory experience refines neural circuits during critical periods of postnatal development1,2,3. Although neuronal activity is…

Patients affected by inflammatory bowel disease (IBD) exhibit compromised intestinal barrier function and decreased mucus…

The HOXA gene locus coordinates body patterning, hematopoiesis, and differentiation. While studying blood phenotype-associated variation…

Barrier organs rely on a limited set of pattern recognition receptors (PRRs) to detect diverse…

Dravet syndrome (DS) is a severe genetic developmental and epileptic encephalopathy usually resulting from mutations…

Three-dimensional genome organization underlies gene regulation, yet how acute hormonal signalling reshapes chromatin structure to…