Publications of the Week Recurrent ZC3H18 Mutations Stabilize Oncogenic Endogenous Retroviral RNA Tanu, T., et al. | July 2, 2026 Endogenous retroviral (ERV) RNA is highly expressed in cancer, suggesting a selective advantage. We identify…karnottJuly 2, 2026 Read More
Publications of the Week NERINE Reveals Rare Variant Associations in Gene Networks Across Phenotypes and Implicates an SNCA-PRL-LRRK2 Subnetwork in Parkinson’s Disease Nazeen, S., et al. | June 30, 2026 Studying the genetic basis of human phenotypes involves two primary strategies. Model-system experiments generate interpretable…karnottJune 30, 2026 Read More
Publications of the Week Probing the Limits of Genetic Recoding Using Multi-Omics-Guided Evolution Nyerges, A., et al. | June 25, 2026 Engineering the genetic code—by reassigning multiple of the 64 natural codons—enables making organisms resistant to…karnottJune 25, 2026 Read More
Publications of the Week Efficient Prime Editing In Vivo and In Vitro Using Lipid Nanoparticles Jiang, A., et al. | June 19, 2026 Prime editing is a versatile clinical genome editing method that enables precise substitutions, small insertions…karnottJune 19, 2026 Read More
Publications of the Week Oesophageal Tissue Screening System for Assessing the Retention and Mucosal Absorption of Biologics Karavasili, C., et al. | June 16, 2026 Drug delivery to the oesophagus poses unique challenges, including rapid transit time due to gravity…karnottJune 16, 2026 Read More
Publications of the Week Am80-Lipid Nanoparticles Serve as an Enteric Mucosal Adjuvant Following Parenteral Immunization with Inactivated Polio Vaccine Eshaghi, B., et al. | June 11, 2026 Enteric pathogens are a major contributor to the global disease burden, necessitating vaccines capable of…karnottJune 11, 2026 Read More
Publications of the Week Long-Lasting Gut Microbiome and Fecal Metabolome Alterations After Colorectal Adenoma Removal and Their Relationship to Colorectal Cancer Nogal, A., et al. | June 8, 2026 Although the gut microbiome is implicated in colorectal cancer (CRC), microbiome and metabolome alterations along…karnottJune 8, 2026 Read More
Publications of the Week Astrocyte Glucocorticoid Receptor Signalling Restricts Neuronal Plasticity Gegenhuber, B., et al. | June 5, 2026 Sensory experience refines neural circuits during critical periods of postnatal development1,2,3. Although neuronal activity is…karnottJune 5, 2026 Read More
Publications of the Week Human Inflammatory Bowel Disease-On-A-Chip for Modelling Disease Progression, Cancer Initiation, and Sex-Specific Effects Özkan, A., et al. | June 3, 2026 Patients affected by inflammatory bowel disease (IBD) exhibit compromised intestinal barrier function and decreased mucus…karnottJune 3, 2026 Read More
Publications of the Week Genetic Variation Reveals a Homeotic Long Noncoding RNA That Modulates Human Hematopoietic Stem Cells Lyu, P., et al. | June 1, 2026 The HOXA gene locus coordinates body patterning, hematopoiesis, and differentiation. While studying blood phenotype-associated variation…karnottJune 1, 2026 Read More