Publications of the Week Secondary Structural Ensembles of the SARS-CoV-2 RNA Genome in Infected Cells Lan, T. C. T., et al. | March 11, 2022 SARS-CoV-2 is a betacoronavirus with a single-stranded, positive-sense, 30-kilobase RNA genome responsible for the ongoing…pthomsonMarch 11, 2022 Read More
Publications of the Week Seipin Forms a Flexible Cage at Lipid Droplet Formation Sites Arlt, H., et al. | March 8, 2022 Lipid droplets (LDs) form in the endoplasmic reticulum by phase separation of neutral lipids. This…pthomsonMarch 8, 2022 Read More
Publications of the Week Molecular Catastrophe, the Peritoneal Cavity, and Ovarian Cancer Prevention Yoon, J. Y., et al. | March 4, 2022 The current theory of carcinogenesis for the deadliest of "ovarian" cancers - high-grade serous carcinoma…pthomsonMarch 4, 2022 Read More
Publications of the Week Characterization of Glycoproteoforms of Integrins α2 and β1 in Megakaryocytes in the Occurrence of JAK2V617F Mutation-Induced Primary Myelofibrosis Gaye, M., et al. | March 1, 2022 Primary myelofibrosis (PMF) is a neoplasm prone to leukemic transformation, for which limited treatment is…pthomsonMarch 1, 2022 Read More
Publications of the Week Assembly of RNA Polymerase II Transcription Initiation Complexes Farnung, L., et al. | February 24, 2022 The first step of eukaryotic gene expression is the assembly of RNA polymerase II and general transcription factors on…pthomsonFebruary 24, 2022 Read More
Publications of the Week Follicular T Cells Optimize the Germinal Center Response to SARS-CoV-2 Protein Vaccination in Mice Cavazzoni, C. B., et al. | February 23, 2022 Follicular helper T (Tfh) cells promote, whereas follicular regulatory T (Tfr) cells restrain, germinal center…pthomsonFebruary 23, 2022 Read More
Publications of the Week Nonenzymatic Assembly of Active Chimeric Ribozymes from Aminoacylated RNA Oligonucleotides Radakovic, A., et al. | February 18, 2022 The emergence of a primordial ribosome from the RNA world would have required access to…pthomsonFebruary 18, 2022 Read More
Publications of the Week Paraxial Mesoderm Organoids Model Development of Human Somites Budjan, C., et al. | February 14, 2022 This week we profile a recent publication in eLife from the lab of Dr. Sahand…pthomsonFebruary 14, 2022 Read More
Publications of the Week Activation Pathways That Drive CD4+ T Cells to Break Tolerance in Autoimmune Diseases Krovi, S. H., et al. | February 11, 2022 Autoimmune diseases are characterized by dysfunctional immune systems that misrecognize self as non-self and cause…pthomsonFebruary 11, 2022 Read More
Publications of the Week Combining p53 mRNA Nanotherapy with Immune Checkpoint Blockade Reprograms the Immune Microenvironment for Effective Cancer Therapy Xiao, Y., et al. | February 10, 2022 Immunotherapy with immune checkpoint blockade (ICB) has shown limited benefits in hepatocellular carcinoma (HCC) and…pthomsonFebruary 10, 2022 Read More