Numerous large-scale efforts have been undertaken to catalog and understand the biology of cancer-associated mutations…
pthomsonApril 13, 2022
The remarkable ability of Mycobacterium tuberculosis to survive attacks from the host immune response and drug treatment…
pthomsonApril 8, 2022
The study and manipulation of T cell receptors (TCRs) is central to multiple fields across…
pthomsonApril 5, 2022
The generation of organoids and tissues with programmable cellular complexity, architecture and function would benefit…
pthomsonApril 1, 2022
Polymorphisms in the human leukocyte antigen (HLA) genes strongly influence autoimmune disease risk. HLA risk alleles may…
pthomsonMarch 30, 2022
The failure of animal models to predict therapeutic responses in humans is a major problem…
pthomsonMarch 25, 2022
The cell stress-responsive transcription factor p53 influences the expression of its target genes and subsequent…
pthomsonMarch 24, 2022
RAS family members are the most frequently mutated oncogenes in human cancers. Although KRAS(G12C)-specific inhibitors…
pthomsonMarch 18, 2022
The Van Galen Laboratory studies molecular mechanisms that sustain the human blood system throughout life.…
pthomsonMarch 15, 2022
