Publications of the Week Inducible De Novo Expression of Neoantigens in Tumor Cells and MiceDamo, M., et al. | August 7, 2020Inducible expression of neoantigens in mice would enable the study of endogenous antigen-specific naïve T…eabramovichAugust 7, 2020 Read More
Publications of the Week Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal CancerCheung, P., et al. | August 5, 2020Although the Hippo transcriptional coactivator YAP is considered oncogenic in many tissues, its roles in…eabramovichAugust 5, 2020 Read More
Publications of the Week CRISPR C-to-G Base Editors for Inducing Targeted DNA Transversions in Human CellsKurt, I.C., et al. | July 30, 2020CRISPR-guided DNA cytosine and adenine base editors are widely used for many applications1,2,3,4 but primarily create…eabramovichJuly 30, 2020 Read More
Publications of the Week Dissecting Cell Type-Specific Metabolism in Pancreatic Ductal AdenocarcinomaLau, A.N., et al. | July 28, 2020This work provides new insight into the metabolic differences between cancer and stromal cells in…eabramovichJuly 28, 2020 Read More
Publications of the Week Local Externalization of Phosphatidylserine Mediates Developmental Synaptic Pruning by MicrogliaScott-Hewitt, N., et al. | July 23, 2020Neuronal circuit assembly requires the fine balance between synapse formation and elimination. Microglia, through the…eabramovichJuly 23, 2020 Read More
Publications of the Week Single-Cell Lineage Tracing Unveils a Role for TCF15 in HaematopoiesisRodriguez-Fraticelli, A.E., et al. | July 21, 2020Bone marrow transplantation therapy relies on the life-long regenerative capacity of haematopoietic stem cells (HSCs)1,2.…eabramovichJuly 21, 2020 Read More
Publications of the Week Systematic Quantitative Analysis of Ribosome Inventory During Nutrient StressAn, H., et al. | July 17, 2020Mammalian cells reorganize their proteomes in response to nutrient stress through translational suppression and degradative…eabramovichJuly 17, 2020 Read More
Publications of the Week The Evolutionarily Conserved piRNA-Producing Locus pi6 Is Required for Male Mouse FertilityWu, PH., et al. | July 14, 2020The results suggest that in mammals — including human beings — a convoluted network of…eabramovichJuly 14, 2020 Read More
Publications of the Week An Ecological Framework to Understand the Efficacy of Fecal Microbiota TransplantationXiao, Y., et al. | July 10, 2020The authors present an ecological framework to understand the efficacy of fecal microbiota transplantation (FMT)…eabramovichJuly 10, 2020 Read More
Publications of the Week Sex Differences in Gene Expression and Regulatory Networks across 29 Human TissuesLopes-Ramos, C.M., et al. | July 7, 2020The authors modeled the network of factors that control gene expression and observed that these…eabramovichJuly 7, 2020 Read More