Publications of the Week Ultra-Sensitive Serial Profiling of SARS-CoV-2 Antigens and Antibodies in Plasma to Understand Disease Progression in COVID-19 Patients with Severe DiseaseOgata, A.F., et al. | September 9, 2020Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over 21 million people worldwide since…eabramovichSeptember 9, 2020 Read More
Publications of the Week Functionally Uncoupled Transcription–Translation in Bacillus subtilisJohnson, G.E., et al. | September 7, 2020Transcription-translation coupling has long been considered a defining feature of the central dogma in bacteria.…eabramovichSeptember 7, 2020 Read More
Publications of the Week A Single Human VH-gene Allows for a Broad-Spectrum Antibody Response Targeting Bacterial Lipopolysaccharides in the BloodSangesland, M., et al. | September 4, 2020B cell receptors (BCRs) display a combination of variable (V)-gene-encoded complementarity determining regions (CDRs) and…eabramovichSeptember 4, 2020 Read More
Publications of the Week Enhancer Dependence of Cell-Type–Specific Gene Expression Increases with Developmental AgeCai, W., et al. | September 2, 2020Gene regulatory logic reflects the occupancy of cis elements by transcription factors and the configuration of promoters…eabramovichSeptember 2, 2020 Read More
Publications of the Week Engineering Designer Beta Cells with a CRISPR-Cas9 Conjugation PlatformLim, D., et al. | August 28, 2020The authors developed a convenient platform to conjugate molecules to Cas9, and using this platform…eabramovichAugust 28, 2020 Read More
Publications of the Week Novel Antimicrobials from Uncultured Bacteria Acting against Mycobacterium tuberculosisQuigley, J., et al. | August 26, 2020Decreasing discovery rates and increasing resistance have underscored the need for novel therapeutic options to…eabramovichAugust 26, 2020 Read More
Publications of the Week Engineered PLGA Microparticles for Long-Term, Pulsatile Release of STING Agonist for Cancer ImmunotherapyLu, X., et al. | August 24, 2020STING agonist – a cancer immunotherapeutic drug – could produce strong antitumor immune responses, but…eabramovichAugust 24, 2020 Read More
Publications of the Week A Distinct Transcriptional Program in Human CAR T Cells Bearing the 4-1BB Signaling Domain Revealed by scRNA-SeqBoroughs, A.C., et al. | August 21, 2020The authors looked at the full transcriptional profile of CAR T cells bearing different signaling…eabramovichAugust 21, 2020 Read More
Publications of the Week A Switch in p53 Dynamics Marks Cells that Escape from DSB-Induced Cell Cycle ArrestTsabar, M., et al. | August 19, 2020In response to DNA damage induced by ionizing irradiation, p53 undergoes oscillatory dynamics with a…eabramovichAugust 19, 2020 Read More
Publications of the Week Epigenetic Transcriptional Reprogramming by WT1 Mediates a Repair Response during Podocyte InjuryEttou, S., et al. | August 17, 2020The authors examined transcriptional reprogramming during podocyte injury. Podocytes are crucial for maintaining filtration in…eabramovichAugust 17, 2020 Read More