Publications of the Week Breast Cancer Prevention by Short-Term Inhibition of TGFβ Signaling Alečković, M., et al. | December 15, 2022 Cancer prevention has a profound impact on cancer-associated mortality and morbidity. We previously identified TGFβ…pthomsonDecember 15, 2022 Read More
Publications of the Week Optimized ACE2 Decoys Neutralize Antibody-Resistant SARS-CoV-2 Variants Through Functional Receptor Mimicry and Treat Infection In Vivo Torchia, J. A., et al. | December 13, 2022 As severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) evolves to escape natural antibodies, it also loses…pthomsonDecember 13, 2022 Read More
Publications of the Week Discovery and Systematic Characterization of Risk Variants and Genes for Coronary Artery Disease in over a Million Participants Aragam, K. G., et al. | December 7, 2022 The discovery of genetic loci associated with complex diseases has outpaced the elucidation of mechanisms…pthomsonDecember 7, 2022 Read More
Publications of the Week Age-Associated Remodeling of T Cell Immunity and Metabolism Han, S., & Georgiev, P., et al. | December 7, 2022 Aging results in remodeling of T cell immunity and is associated with poor clinical outcomes in…pthomsonDecember 7, 2022 Read More
Publications of the Week Pre-T Cell Receptor Self-MHC Sampling Restricts Thymocyte Dedifferentiation Duke-Cohan, J.S., et al. | December 2, 2022 Programming T lymphocytes to distinguish self from non-self is a vital, multi-step process arising in…pthomsonDecember 2, 2022 Read More
Publications of the Week The Future of Engineered Immune Cell Therapies Irvine, D., et al. | November 28, 2022 Immune cells are being engineered to recognize and respond to disease states, acting as a…pthomsonNovember 28, 2022 Read More
Publications of the Week RBPMS2 Is a Myocardial-Enriched Splicing Regulator Required for Cardiac Function Akerberg, a. A., et al. | November 25, 2022 RBPs (RNA-binding proteins) perform indispensable functions in the post-transcriptional regulation of gene expression. Numerous RBPs…pthomsonNovember 25, 2022 Read More
Publications of the Week Identification of TFPI as a Receptor Reveals Recombination-Driven Receptor Switching in Clostridioides difficile Toxin B Variants Tian, S., et al. | November 25, 2022 Toxin B (TcdB) is a major exotoxin responsible for diseases associated with Clostridioides difficile infection. Its sequence…pthomsonNovember 25, 2022 Read More
Publications of the Week Bioelectric Regulation of Intestinal Stem Cells Petsakou, A., et al. | November 17, 2022 Ion channels, pumps, and exchangers regulate the transport of ions, such as Na+, Cl–, K+,…pthomsonNovember 17, 2022 Read More
Publications of the Week Velcrin-Induced Selective Cleavage of tRNALeu(TAA) by SLFN12 Causes Cancer Cell Death Lee, S., et al. | November 17, 2022 Dr. Heidi Greulich's group is interested in understanding the mechanism of action of velcrin compounds,…pthomsonNovember 17, 2022 Read More