Publications of the Week Proteolethargy Is a Pathogenic Mechanism in Chronic DiseaseDall’Agnese, A., et al. | December 4, 2024The pathogenic mechanisms of many diseases are well understood at the molecular level, but there…karnottDecember 4, 2024 Read More
Publications of the Week Jellyfish for the Study of Nervous System Evolution and FunctionCunningham, K., et al. | December 2, 2024Jellyfish comprise a diverse clade of free-swimming predators that arose prior to the Cambrian explosion.…karnottDecember 2, 2024 Read More
Publications of the Week Evolving Cell States and Oncogenic Drivers During the Progression of IDH-Mutant GliomasWu, J., et al. | November 29, 2024Isocitrate dehydrogenase (IDH) mutants define a class of gliomas that are initially slow-growing but inevitably…karnottNovember 29, 2024 Read More
Publications of the Week Tumor Integrin-Targeted Glucose Oxidase Enzyme Promotes ROS-Mediated Cell Death That Combines with Interferon Alpha Therapy for Tumor ControlStinson, J., et al. | November 27, 2024Although heightened intratumoral levels of reactive oxygen species (ROS) are typically associated with a suppressive…karnottNovember 27, 2024 Read More
Publications of the Week Cephalopod-Inspired Jetting Devices for Gastrointestinal Drug DeliveryArrick, G., et al. | November 25, 2024Needle-based injections currently enable the administration of a wide range of biomacromolecule therapies across the…karnottNovember 25, 2024 Read More
Publications of the Week Regulated GATA1 Expression as a Universal Gene Therapy for Diamond-Blackfan AnemiaVoit, R., et al. | November 20, 2024This week, we profile a recent publication in Cell Stem Cell by Dr. Vijay Sankaran…karnottNovember 20, 2024 Read More
Publications of the Week Somatic Mosaicism in Schizophrenia Brains Reveals Prenatal Mutational ProcessesMaury, E., et al. | November 18, 2024Somatic mutations during brain development have been associated with several neurological disorders. Maury et al. performed…karnottNovember 18, 2024 Read More
Publications of the Week Brca1 Haploinsufficiency Promotes Early Tumor Onset and Epigenetic Alterations in a Mouse Model of Hereditary Breast CancerMan-Chung Li, C., | November 15, 2024Germline BRCA1 mutation carriers face a high breast cancer risk; however, the underlying mechanisms for this risk…karnottNovember 15, 2024 Read More
Publications of the Week Heterogeneous Genetic Architectures of Prostate Cancer Susceptibility in Sub-Saharan AfricaJanivara, R., et al. | November 13, 2024Men of African descent have the highest prostate cancer incidence and mortality rates, yet the…karnottNovember 13, 2024 Read More
Publications of the Week Immune Responses in Checkpoint Myocarditis Across Heart, Blood, and TumourBlum, S., et al. | November 11, 2024Immune checkpoint inhibitors are widely used anticancer therapies1 that can cause morbid and potentially fatal…karnottNovember 11, 2024 Read More