Publications of the Week A Noncoding Regulatory Variant in IKZF1 Increases Acute Lymphoblastic Leukemia Risk in Hispanic/Latino Childrende Smith, A., et al. | March 28, 2024Hispanic/Latino children have the highest risk of acute lymphoblastic leukemia (ALL) in the US compared…karnottMarch 28, 2024 Read More
Publications of the Week Derivation and External Validation of a Simple Risk Score for Predicting Severe Acute Kidney Injury After Intravenous Cisplatin: Cohort StudyGupta, S., et al. | March 27, 2024The primary outcome was CP-AKI, defined as a twofold or greater increase in serum creatinine…karnottMarch 27, 2024 Read More
Publications of the Week Branched Chemically Modified Poly(A) Tails Enhance the Translation Capacity of mRNAChen, H., et al. | March 25, 2024Although messenger RNA (mRNA) has proved effective as a vaccine, its potential as a general…karnottMarch 25, 2024 Read More
Publications of the Week Single-Cell Dissection of the Human Motor and Prefrontal Cortices in ALS and FTLDPineda, S., et al. | March 22, 2024Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) share many clinical, pathological, and genetic…karnottMarch 22, 2024 Read More
Publications of the Week Human Lung Cancer Harbors Spatially Organized Stem-Immunity Hubs Associated with Response to ImmunotherapyChen, J., et al. | March 21, 2024The organization of immune cells in human tumors is not well understood. Immunogenic tumors harbor…karnottMarch 21, 2024 Read More
Publications of the Week Continuous Evolution of Compact Protein Degradation Tags Regulated by Selective Molecular GluesMercer, J., et al. | March 19, 2024Degron tags enable rapid and tunable control of target protein levels using small molecules. The…karnottMarch 19, 2024 Read More
Publications of the Week High-Throughput Evaluation of Genetic Variants with Prime Editing Sensor LibrariesGould, S., et al. | March 15, 2024Tumor genomes often harbor a complex spectrum of single nucleotide alterations and chromosomal rearrangements that…karnottMarch 15, 2024 Read More
Publications of the Week Single Nuclei Transcriptomics in Human and Non-Human Primate Striatum in Opioid Use DisorderPhan, B., et al. | March 11, 2024In brain, the striatum is a heterogenous region involved in reward and goal-directed behaviors. Striatal…karnottMarch 11, 2024 Read More
Publications of the Week Proteogenomic Characterization of Primary Colorectal Cancer and Metastatic Progression Identifies Proteome-Based Subtypes and SignaturesTanaka, A., et al. | March 8, 2024Metastatic progression of colorectal adenocarcinoma (CRC) remains poorly understood and poses significant challenges for treatment.…karnottMarch 8, 2024 Read More
Publications of the Week SOX17 Enables Immune Evasion of Early Colorectal Adenomas and CancersGoto, N., et al. | March 6, 2024A hallmark of cancer is the avoidance of immune destruction. This process has been primarily…karnottMarch 6, 2024 Read More