Publications of the Week FHL2 Anchors Mitochondria to Actin and Adapts Mitochondrial Dynamics to Glucose SupplyBasu, H., et al. | August 13, 2021Mitochondrial movement and distribution are fundamental to their function. Here we report a mechanism that…pthomsonAugust 13, 2021 Read More
Publications of the Week Yap/Taz Inhibit Goblet Cell Fate to Maintain Lung Epithelial HomeostasisHicks-Berthet, J., et al. | August 9, 2021Read the Publication This week we profile a recent publication in Cell Reports from Dr.…pthomsonAugust 9, 2021 Read More
Publications of the Week Genes with Specificity for Expression in the Round Cell Layer of the Growth Plate Are Enriched in Genomewide Association Study (GWAS) of Human HeightRenthal, N. E., and Nakka, P., et al. | August 6, 2021Human adult height reflects the outcome of childhood skeletal growth. Growth plate (epiphyseal) chondrocytes are…pthomsonAugust 6, 2021 Read More
Publications of the Week Neurotensin Is an Anti-Thermogenic Peptide Produced by Lymphatic Endothelial CellsLi, J., et al. | August 2, 2021Dr. Evan Rosen's lab is focused on understanding how adipose tissue functions normally, and how…pthomsonAugust 2, 2021 Read More
Publications of the Week Dynamic BH3 Profiling Identifies Active BH3 Mimetic Combinations in Non-Small Cell Lung CancerPotter, D. S., et al. | July 30, 2021Conventional chemotherapy is still of great utility in oncology and rationally constructing combinations with it…pthomsonJuly 30, 2021 Read More
Publications of the Week cGAS-Like Receptors Sense RNA and Control 3′2′-cGAMP Signaling in DrosophilaSlavik, K. M., et al. | July 27, 2021Cyclic GMP–AMP synthase (cGAS) is a cytosolic DNA sensor that produces the second messenger 2′3′-cGAMP…pthomsonJuly 27, 2021 Read More
Publications of the Week Extracellular Domain Shedding of the ALK Receptor Mediates Neuroblastoma Cell MigrationHuang, H., et al. | July 22, 2021Although activating mutations of the anaplastic lymphoma kinase (ALK) membrane receptor occur in ∼10% of…pthomsonJuly 22, 2021 Read More
Publications of the Week Haplotype-Resolved Germline and Somatic Alterations in Renal Medullary CarcinomasTan, K.-T., et al. | July 21, 2021Renal medullary carcinomas (RMCs) are rare kidney cancers that occur in adolescents and young adults…pthomsonJuly 21, 2021 Read More
Publications of the Week Actin-Related Protein (Arp) 2/3 Complex Plays a Critical Role in the Aquaporin-2 Exocytotic PathwayLiu, C.-C. S., et al. | July 16, 2021The trafficking of proteins such as aquaporin-2 (AQP2) in the exocytotic pathway requires an active…pthomsonJuly 16, 2021 Read More
Publications of the Week Nephrotoxicity Assessment with Human Kidney Tubuloids using Spherical Nucleic Acid-Based mRNA NanoflaresWiraja, C., et al. | July 14, 2021Drug-induced nephrotoxicity represents an important cause of acute kidney injury with associated patient morbidity and…pthomsonJuly 14, 2021 Read More