Publications of the Week

The rational design of receptor agonists to control cell signaling is an emerging strategy for…

Meiotic failure is a major cause of infertility, but the lack of an in vitro…

The earliest molecular changes in Alzheimer’s disease (AD) are poorly understood1,2,3,4,5. Here we show that…

In vivo CRISPR screens in CD8+ T cells have previously uncovered targets for cancer immunotherapy;…

Parkinson’s disease (PD) is characterized by inclusions of α-synuclein (α-syn) and mitochondrial dysfunction in dopaminergic…

The U.S. Food and Drug Administration recently approved the first CRISPR-Cas9 therapy, making genome editing…

Lung adenocarcinomas (LUAD) are a pressing global health problem with enduring lethality and rapidly shifting…

Alternating hemiplegia of childhood (AHC) is a neurodevelopmental disorder with no disease-modifying treatment. Mutations in…

Filoviruses such as Ebola virus (EBOV) give rise to frequent epidemics with high case fatality…

To meet the brain’s moment-to-moment energy demand, neural activation rapidly increases local blood flow. This…