Publications of the Week Targeting Rictor Sensitizes SMAD4-Negative Colon Cancer to Irinotecan Wong, C., K., et al. | January 15, 2020 Deciphering molecular targets to enhance sensitivity to chemotherapy is becoming a priority for effectively treating…sciencecityJanuary 15, 2020 Read More
Publications of the Week Generation of Mesenchyme Free Intestinal Organoids from Human Induced Pluripotent Stem Cells Mithal, A., et al. | January 14, 2020 Efficient generation of human induced pluripotent stem cell (hiPSC)-derived human intestinal organoids (HIOs) would facilitate…sciencecityJanuary 14, 2020 Read More
Publications of the Week Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVS Chao C., et al. | January 13, 2020 My lab is focused on the identification of molecular mechanisms by which the environment, the…sciencecityJanuary 13, 2020 Read More
Publications of the Week In Vitro Characterization of the Human Segmentation Clock Diaz-Cuadros, M., et al. | January 10, 2020 The segmental organization of the vertebral column is established early in embryogenesis, when pairs of…sciencecityJanuary 10, 2020 Read More
Publications of the Week Selective Induction of Antibody Effector Functional Responses Using MF59-Adjuvanted Vaccination Boudreau, C., M., et al. | January 8, 2020 Seasonal and pandemic influenza infection remains a major public health concern worldwide. Driving robust humoral…sciencecityJanuary 8, 2020 Read More
Publications of the Week C-Cbl Targets PD-1 in Immune Cells for Proteasomal Degradation and Modulates Colorectal Tumor Growth Lyle, C., et al. | January 6, 2020 Casitas B lymphoma (c-Cbl) is an E3 ubiquitin ligase and a negative regulator of colorectal…sciencecityJanuary 6, 2020 Read More
Publications of the Week IL-33 Signaling Alters Regulatory T Cell Diversity in Support of Tumor Development Li, A., et al. | December 20, 2019 Regulatory T cells (Tregs) can impair anti-tumor immune responses and are associated with poor prognosis in…sciencecityDecember 20, 2019 Read More
Publications of the Week Domain-specific Quantification of Prion Protein in Cerebrospinal Fluid by Targeted Mass Spectrometry Minikel, E., V., et al | December 20, 2019 Therapies currently in preclinical development for prion disease seek to lower prion protein (PrP) expression…sciencecityDecember 20, 2019 Read More
Publications of the Week A Strategic Approach for Fluorescence Imaging of Membrane Proteins in a Native-like Environment Swiecicki, J., M., et al. | December 20, 2019 Biological membranes are complex barriers in which membrane proteins and thousands of lipidic species participate…sciencecityDecember 20, 2019 Read More
Publications of the Week Toward a Common Coordinate Framework for the Human Body Rood, E., J., et al. | December 19, 2019 Understanding the genetic and molecular drivers of phenotypic heterogeneity across individuals is central to biology.…sciencecityDecember 19, 2019 Read More