Publications of the Week Neural Circuits for Evidence Accumulation and Decision Making in Larval Zebrafish Bahl, A., et al. | December 6, 2019 To make appropriate decisions, animals need to accumulate sensory evidence. Simple integrator models can explain…sciencecityDecember 6, 2019 Read More
Publications of the Week Immune Recognition of Microbial Metabolites Garrett, W.S. | December 3, 2019 Mucosal immunology research continues its fascination with microbial metabolites. In 2019, researchers uncovered extended functions…sciencecityDecember 3, 2019 Read More
Publications of the Week Oral Ionic Liquid for the Treatment of Diet-Induced Obesity Nurunnabi, M., et al. | November 27, 2019 Obesity is considered a strong factor in many chronic diseases, including heart disease, diabetes, and…sciencecityNovember 27, 2019 Read More
Publications of the Week Human iPSC-Derived Microglia Assume a Primary Microglia-Like State after Transplantation into the Neonatal Mouse Brain Svodoba, D., S., et al. | November 27, 2019 Microglia, the resident immune cells of the brain, are known to be crucial for normal…sciencecityNovember 27, 2019 Read More
Publications of the Week Delivering Genes across the Blood-Brain Barrier: LY6A, a Novel Cellular Receptor for Aav-PHP.B Capsids Huang, Q., et al. | November 22, 2019 The engineered AAV-PHP.B family of adeno-associated virus efficiently delivers genes throughout the mouse central nervous…sciencecityNovember 22, 2019 Read More
Publications of the Week A New Antibiotic Selectively Kills Gram-Negative Pathogens Imai, Y., et al. | November 21, 2019 The current need for novel antibiotics is especially acute for drug-resistant Gram-negative pathogens. These microorganisms…sciencecityNovember 21, 2019 Read More
Publications of the Week T Lymphocytes and Cytotoxic Astrocyte Blebs Correlate Across Autism Brains DiStasio, M., M., et al. | November 15, 2019 Autism spectrum disorder (ASD) affects 1 in 59 children, yet except for rare genetic causes,…sciencecityNovember 15, 2019 Read More
Publications of the Week Retro-2 Protects Cells from Ricin Toxicity by Inhibiting ASNA1-Mediated Er Targeting and Insertion of Tail-Anchored Proteins Morgens, D., W., et al. | November 13, 2019 The small molecule Retro-2 prevents ricin toxicity through a poorly-defined mechanism of action (MOA), which…sciencecityNovember 13, 2019 Read More
Publications of the Week Inducible Histone K-to-M Mutations Are Dynamic Tools to Probe the Physiological Role of Site-Specific Histone Methylation In Vitro and In Vivo Brumbaugh, J., et al. | November 8, 2019 Development and differentiation are associated with profound changes to histone modifications, yet their in vivo…sciencecityNovember 8, 2019 Read More
Publications of the Week A Generalized HIV Vaccine Design Strategy for Priming of Broadly Neutralizing Antibody Responses Steichen, J., M., et al. | November 7, 2019 Vaccine induction of broadly neutralizing antibodies (bnAbs) to human immunodeficiency virus (HIV) remains a major…sciencecityNovember 7, 2019 Read More