Publications of the Week Discovery of Antibiotics That Selectively Kill Metabolically Dormant Bacteria Zheng, E., et al. | April 10, 2024 There is a need to discover and develop non-toxic antibiotics that are effective against metabolically…karnottApril 10, 2024 Read More
Publications of the Week Direct Interrogation of Context-Dependent GPCR Activity with a Universal Biosensor Platform Janicot, R., et al. | April 8, 2024 G protein-coupled receptors (GPCRs) are the largest family of druggable proteins encoded in the human…karnottApril 8, 2024 Read More
Publications of the Week Gut Microbiome and Metabolome Profiling in Framingham Heart Study Reveals Cholesterol-Metabolizing Bacteria Li, C., et al. | April 4, 2024 Accumulating evidence suggests that cardiovascular disease (CVD) is associated with an altered gut microbiome. Our…karnottApril 4, 2024 Read More
Publications of the Week Skin Biopsy Detection of Phosphorylated α-Synuclein in Patients with Synucleinopathies Gibbons, C., et al. | April 3, 2024 Can skin biopsy detect phosphorylated α-synuclein in individuals with synucleinopathies such as Parkinson disease (PD),…karnottApril 3, 2024 Read More
Publications of the Week Neutrophils Bearing Adhesive Polymer Micropatches as a Drug-Free Cancer Immunotherapy Kumbhojkar, N., et al. | April 2, 2024 Tumour-associated neutrophils can exert antitumour effects but can also assume a pro-tumoural phenotype in the…karnottApril 2, 2024 Read More
Publications of the Week A Noncoding Regulatory Variant in IKZF1 Increases Acute Lymphoblastic Leukemia Risk in Hispanic/Latino Children de Smith, A., et al. | March 28, 2024 Hispanic/Latino children have the highest risk of acute lymphoblastic leukemia (ALL) in the US compared…karnottMarch 28, 2024 Read More
Publications of the Week Derivation and External Validation of a Simple Risk Score for Predicting Severe Acute Kidney Injury After Intravenous Cisplatin: Cohort Study Gupta, S., et al. | March 27, 2024 The primary outcome was CP-AKI, defined as a twofold or greater increase in serum creatinine…karnottMarch 27, 2024 Read More
Publications of the Week Branched Chemically Modified Poly(A) Tails Enhance the Translation Capacity of mRNA Chen, H., et al. | March 25, 2024 Although messenger RNA (mRNA) has proved effective as a vaccine, its potential as a general…karnottMarch 25, 2024 Read More
Publications of the Week Single-Cell Dissection of the Human Motor and Prefrontal Cortices in ALS and FTLD Pineda, S., et al. | March 22, 2024 Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) share many clinical, pathological, and genetic…karnottMarch 22, 2024 Read More
Publications of the Week Human Lung Cancer Harbors Spatially Organized Stem-Immunity Hubs Associated with Response to Immunotherapy Chen, J., et al. | March 21, 2024 The organization of immune cells in human tumors is not well understood. Immunogenic tumors harbor…karnottMarch 21, 2024 Read More