Publications of the Week Glucose Metabolism and Pyruvate Carboxylase Enhance Glutathione Synthesis and Restrict Oxidative Stress in Pancreatic IsletsFu, A., et al. | December 3, 2021Glucose metabolism modulates the islet β cell responses to diabetogenic stress, including inflammation. Here, we…pthomsonDecember 3, 2021 Read More
Publications of the Week Intercellular Nanotubes Mediate Mitochondrial Trafficking between Cancer and Immune CellsSaha, T., et al. | December 2, 2021Cancer progresses by evading the immune system. Elucidating diverse immune evasion strategies is a critical…pthomsonDecember 2, 2021 Read More
Publications of the Week Reprogramming NK Cells and Macrophages via Combined Antibody and Cytokine Therapy Primes Tumors for Elimination by Checkpoint BlockadeWang, C., et al. | November 26, 2021Treatments aiming to augment immune checkpoint blockade (ICB) in cancer often focus on T cell immunity,…pthomsonNovember 26, 2021 Read More
Publications of the Week A Tissue-Bioengineering Strategy for Modeling Rare Human Kidney Diseases In VivoHernandez, J. O. R., & Wang, X., et al. | November 22, 2021A recent publication in Nature Communications showcases a bioengineering approach to model renal diseases associated…pthomsonNovember 22, 2021 Read More
Publications of the Week Sensory Transduction Is Required for Normal Development and Maturation of Cochlear Inner Hair Cell SynapsesLee, J., et al. | November 19, 2021Acoustic overexposure and aging can damage auditory synapses in the inner ear by a process…pthomsonNovember 19, 2021 Read More
Publications of the Week Indoleamine 2,3-dioxygenase-1, a Novel Therapeutic Target for Post-Vascular Injury Thrombosis in CKDWalker, J. A., et al. | November 15, 2021CKD, characterized by retained uremic solutes, is a strong and independent risk factor for thrombosis…pthomsonNovember 15, 2021 Read More
Publications of the Week Inner Nuclear Protein Matrin-3 Coordinates Cell Differentiation by Stabilizing Chromatin ArchitectureCha, H. J., et al. | November 12, 2021Precise control of gene expression during differentiation relies on the interplay of chromatin and nuclear…pthomsonNovember 12, 2021 Read More
Publications of the Week Lung Proteomic Biomarkers Associated with Chronic Obstructive Pulmonary DiseaseZyang. Y.-H., et al. | November 8, 2021Identifying protein biomarkers for chronic obstructive pulmonary disease (COPD) has been challenging. Most previous studies…pthomsonNovember 8, 2021 Read More
Publications of the Week De Novo Identification of Mammalian Ciliary Motility Proteins Using Cryo-EMGui, M., Farley, H., & Anujan, P., et al. | November 5, 2021Dynein-decorated doublet microtubules (DMTs) are critical components of the oscillatory molecular machine of cilia, the…pthomsonNovember 5, 2021 Read More
Publications of the Week Discovery of Autoantibodies Targeting Nephrin in Minimal Change Disease Supports a Novel Autoimmune EtiologyWatts, A., et al. | November 5, 2021Failure of the glomerular filtration barrier, primarily by loss of slit diaphragm architecture, underlies nephrotic…pthomsonNovember 5, 2021 Read More