Publications of the Week

Degron tags enable rapid and tunable control of target protein levels using small molecules. The…

Tumor genomes often harbor a complex spectrum of single nucleotide alterations and chromosomal rearrangements that…

In brain, the striatum is a heterogenous region involved in reward and goal-directed behaviors. Striatal…

Metastatic progression of colorectal adenocarcinoma (CRC) remains poorly understood and poses significant challenges for treatment.…

A hallmark of cancer is the avoidance of immune destruction. This process has been primarily…

Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes1,2 and…

Metazoan gene expression regulation involves pausing of RNA polymerase (Pol II) in the promoter-proximal region…

The phase III JAVELIN Renal 101 trial demonstrated prolonged progression-free survival (PFS) in patients (N = 886)…

The prevalence of youth-onset type 2 diabetes (T2D) and childhood obesity has been rising steadily1,…

Combining docetaxel and capivasertib had increased activity in PTEN null and WT prostate tumour models…