Publications of the Week Characterization of Glycoproteoforms of Integrins α2 and β1 in Megakaryocytes in the Occurrence of JAK2V617F Mutation-Induced Primary MyelofibrosisGaye, M., et al. | March 1, 2022Primary myelofibrosis (PMF) is a neoplasm prone to leukemic transformation, for which limited treatment is…pthomsonMarch 1, 2022 Read More
Publications of the Week Assembly of RNA Polymerase II Transcription Initiation ComplexesFarnung, L., et al. | February 24, 2022The first step of eukaryotic gene expression is the assembly of RNA polymerase II and general transcription factors on…pthomsonFebruary 24, 2022 Read More
Publications of the Week Follicular T Cells Optimize the Germinal Center Response to SARS-CoV-2 Protein Vaccination in MiceCavazzoni, C. B., et al. | February 23, 2022Follicular helper T (Tfh) cells promote, whereas follicular regulatory T (Tfr) cells restrain, germinal center…pthomsonFebruary 23, 2022 Read More
Publications of the Week Nonenzymatic Assembly of Active Chimeric Ribozymes from Aminoacylated RNA OligonucleotidesRadakovic, A., et al. | February 18, 2022The emergence of a primordial ribosome from the RNA world would have required access to…pthomsonFebruary 18, 2022 Read More
Publications of the Week Paraxial Mesoderm Organoids Model Development of Human SomitesBudjan, C., et al. | February 14, 2022This week we profile a recent publication in eLife from the lab of Dr. Sahand…pthomsonFebruary 14, 2022 Read More
Publications of the Week Activation Pathways That Drive CD4+ T Cells to Break Tolerance in Autoimmune DiseasesKrovi, S. H., et al. | February 11, 2022Autoimmune diseases are characterized by dysfunctional immune systems that misrecognize self as non-self and cause…pthomsonFebruary 11, 2022 Read More
Publications of the Week Combining p53 mRNA Nanotherapy with Immune Checkpoint Blockade Reprograms the Immune Microenvironment for Effective Cancer TherapyXiao, Y., et al. | February 10, 2022Immunotherapy with immune checkpoint blockade (ICB) has shown limited benefits in hepatocellular carcinoma (HCC) and…pthomsonFebruary 10, 2022 Read More
Publications of the Week GABA Transmission from mAL Interneurons Regulates Aggression in Drosophila MalesSengupta, S., et al. | February 4, 2022Aggression is dependent on the sex of the conspecific in almost all animal species. But…pthomsonFebruary 4, 2022 Read More
Publications of the Week Human Airway Lineages Derived from Pluripotent Stem Cells Reveal the Epithelial Responses to SARS-CoV-2 InfectionWang, R., et al. | January 31, 2022This work is a collaborative effort between the Hawkins, Kotton, Mühlberger and Wang laboratories. The…pthomsonJanuary 31, 2022 Read More
Publications of the Week NK Cells in the Brain: Implications for Brain Tumor Development and TherapyBalatsoukas, A., et al. | January 28, 2022Natural killer (NK) cell therapies are finding their way as promising tools for more effective…pthomsonJanuary 28, 2022 Read More