Publications of the Week

Pediatric cancers are frequently driven by genomic alterations that result in aberrant transcription factor activity.…

To withstand a hostile cellular environment and replicate, viruses must sense, interpret, and respond to…

In eukaryotes, the Suv39 family of proteins tri-methylate lysine 9 of histone H3 (H3K9me) to…

Sudden infant death syndrome (SIDS) is the leading cause of post-neonatal infant mortality, but the…

Broadly neutralizing antibodies (bnAbs) targeting the hemagglutinin (HA) stem of influenza A viruses (IAVs) tend…

In response to pathogen infection, gasdermin (GSDM) proteins form membrane pores that induce a host…

Phosphoinositide-3-kinase-γ (PI3Kγ) is implicated as a target to repolarize tumour-associated macrophages and promote antitumour immune…

Developing vehicles that efficiently deliver genes throughout the human central nervous system (CNS) will broaden…

CEP290-associated inherited retinal degeneration causes severe early-onset vision loss due to pathogenic variants in CEP290.…

Phosphorylation of proteins on tyrosine (Tyr) residues evolved in metazoan organisms as a mechanism of…