Publications of the Week Genome-Wide Association Study Identifies Human Genetic Variants Associated with Fatal Outcome from Lassa Fever Kotliar, D., et al. | February 19, 2024 Infection with Lassa virus (LASV) can cause Lassa fever, a haemorrhagic illness with an estimated…karnottFebruary 19, 2024 Read More
Publications of the Week Enhancing Cancer Immunotherapy via Inhibition of Soluble Epoxide Hydrolase Kelly, A., et al. | February 13, 2024 While immunotherapy is a front-line cancer treatment, unresolved chronic inflammation and toxicities often limit its…karnottFebruary 13, 2024 Read More
Publications of the Week Direct Reprogramming of Non-limb Fibroblasts to Cells with Properties of Limb Progenitors Atsuta, Y., et al. | February 12, 2024 The early limb bud consists of mesenchymal limb progenitors derived from the lateral plate mesoderm…karnottFebruary 12, 2024 Read More
Publications of the Week Cryptic Splicing of Stathmin-2 and UNC13A mRNAs Is a Pathological Hallmark of TDP-43-Associated Alzheimer’s Disease Almeida Quadros, A., et al. | February 9, 2024 Nuclear clearance and cytoplasmic accumulations of the RNA-binding protein TDP-43 are pathological hallmarks in almost…karnottFebruary 9, 2024 Read More
Publications of the Week Improved Immunostaining of Nanostructures and Cells in Human Brain Specimens Through Expansion-Mediated Protein Decrowding Valdes, P., et al. | February 7, 2024 Proteins are densely packed in cells and tissues, where they form complex nanostructures. Expansion microscopy…karnottFebruary 7, 2024 Read More
Publications of the Week CAG Repeat Expansions Create Splicing Acceptor Sites and Produce Aberrant Repeat-Containing RNAs Anderson, R., et al. | February 5, 2024 Expansions of CAG trinucleotide repeats cause several rare neurodegenerative diseases. The disease-causing repeats are translated…karnottFebruary 5, 2024 Read More
Publications of the Week HIV-1 Capsids Enter the Fg Phase of Nuclear Pores like a Transport Receptor Fu, L., et al. | February 2, 2024 HIV-1 infection requires nuclear entry of the viral genome. Previous evidence suggests that this entry…karnottFebruary 2, 2024 Read More
Publications of the Week AAV1-hOTOF Gene Therapy for Autosomal Recessive Deafness 9: A Single-Arm Trial Lv, J., et al. | February 1, 2024 Autosomal recessive deafness 9, caused by mutations of the OTOF gene, is characterised by congenital or prelingual,…karnottFebruary 1, 2024 Read More
Publications of the Week Enhancing Antibody Responses by Multivalent Antigen Display on Thymus-Independent DNA Origami Scaffolds Wamhoff, E., et al. | January 30, 2024 Protein-based virus-like particles (P-VLPs) are commonly used to spatially organize antigens and enhance humoral immunity…karnottJanuary 30, 2024 Read More
Publications of the Week Priming Agents Transiently Reduce the Clearance of Cell-Free DNA to Improve Liquid Biopsies Martin-Alonso, C., et al. | January 26, 2024 Liquid biopsy for tumor analysis offers the potential for noninvasive access using a blood draw…karnottJanuary 26, 2024 Read More