Publications of the Week

Therapeutic small interfering RNA (siRNA) requires sugar and backbone modifications to inhibit nuclease degradation. However,…

KMT2C and KMT2D, encoding histone H3 lysine 4 methyltransferases, are among the most commonly mutated…

Although chimeric antigen receptor (CAR) T cell therapies have demonstrated promising clinical outcomes, durable remissions…

The heterogeneity of protein-rich inclusions and its significance in neurodegeneration is poorly understood. Standard patient-derived…

The choroid plexus (ChP) is a vital brain barrier and source of cerebrospinal fluid (CSF).…

Changes in the amount of daylight (photoperiod) alter physiology and behaviour1,2. Adaptive responses to seasonal…

Every day, hundreds of thousands of people undergo general anesthesia. One hypothesis is that anesthesia…

Natural killer, or NK, cells endowed with memory-like abilities and armed with a novel chimeric…

Vaccination can help prevent infection and can also be used to treat cancer, allergy, and…

Although chimeric antigen receptor (CAR) T cell therapy represents a transformative immunotherapy, it is also…