Publications of the Week Dysregulation of Platelet Serotonin, 14–3–3, and Gpix in Sudden Infant Death Syndrome Frelinger, A., et al. | May 29, 2024 Sudden infant death syndrome (SIDS) is the leading cause of post-neonatal infant mortality, but the…karnottMay 29, 2024 Read More
Publications of the Week Eliciting a Single Amino Acid Change by Vaccination Generates Antibody Protection Against Group 1 and Group 2 Influenza a Viruses Ray, R., et al. | May 27, 2024 Broadly neutralizing antibodies (bnAbs) targeting the hemagglutinin (HA) stem of influenza A viruses (IAVs) tend…karnottMay 27, 2024 Read More
Publications of the Week Structure and Assembly of a Bacterial Gasdermin Pore Johnson, A., et al. | May 24, 2024 In response to pathogen infection, gasdermin (GSDM) proteins form membrane pores that induce a host…karnottMay 24, 2024 Read More
Publications of the Week Targetable Leukaemia Dependency on Noncanonical PI3Kγ Signalling Luo, Q., et al. | May 22, 2024 Phosphoinositide-3-kinase-γ (PI3Kγ) is implicated as a target to repolarize tumour-associated macrophages and promote antitumour immune…karnottMay 22, 2024 Read More
Publications of the Week An AAV Capsid Reprogrammed to Bind Human Transferrin Receptor Mediates Brain-Wide Gene Delivery Huang, Q., et al. | May 21, 2024 Developing vehicles that efficiently deliver genes throughout the human central nervous system (CNS) will broaden…karnottMay 21, 2024 Read More
Publications of the Week Gene Editing for CEP290-Associated Retinal Degeneration Pierce, E., et al. | May 16, 2024 CEP290-associated inherited retinal degeneration causes severe early-onset vision loss due to pathogenic variants in CEP290.…karnottMay 16, 2024 Read More
Publications of the Week The Intrinsic Substrate Specificity of the Human Tyrosine Kinome Yaron-Barir, T., et al. | May 13, 2024 Phosphorylation of proteins on tyrosine (Tyr) residues evolved in metazoan organisms as a mechanism of…karnottMay 13, 2024 Read More
Publications of the Week Eliciting a Single Amino Acid Change by Vaccination Generates Antibody Protection Against Group 1 and Group 2 Influenza a Viruses Ray, R., et al. | May 8, 2024 Broadly neutralizing antibodies (bnAbs) targeting the hemagglutinin (HA) stem of influenza A viruses (IAVs) tend…karnottMay 8, 2024 Read More
Publications of the Week Disease Related Changes in ATAC-Seq of iPSC-Derived Motor Neuron Lines from ALS Patients and Controls Tsitkov, S., et al. | May 6, 2024 Amyotrophic Lateral Sclerosis (ALS), like many other neurodegenerative diseases, is highly heritable, but with only…karnottMay 6, 2024 Read More
Publications of the Week Epigenetic Modulation Through BET Bromodomain Inhibitors as a Novel Therapeutic Strategy for Progranulin-Deficient Frontotemporal Dementia Rosenthal, Z., et al. | May 3, 2024 Frontotemporal dementia (FTD) is a debilitating neurodegenerative disorder with currently no disease-modifying treatment options available.…karnottMay 3, 2024 Read More