Publications of the Week Central Memory T Cells Are the Most Effective Precursors of Resident Memory T Cells in Human SkinMatos, T. R., et al. | April 30, 2022Skin resident memory T cells (TRM) are important mediators of frontline immunity in response to…pthomsonApril 30, 2022 Read More
Publications of the Week Non-cleavable Hinge Enhances Avidity and Expansion of CAR-T Cells for Acute Myeloid LeukemiaLeick, M. B., et al. | April 28, 2022Chimeric antigen receptor (CAR) T cell therapy is effective in lymphoid malignancies, but there has been limited…pthomsonApril 28, 2022 Read More
Publications of the Week Genome-Wide Pleiotropy Analysis of Coronary Artery Disease and Pneumonia Identifies Shared Immune PathwaysYu, Z., et al. | April 22, 2022Coronary artery disease (CAD) remains the leading cause of death despite scientific advances. Elucidating shared…pthomsonApril 22, 2022 Read More
Publications of the Week ADAR1 and Its Implications in Cancer Development and TreatmentBaker, A., et al. | April 19, 2022The epitranscriptome represents an emerging novel layer of gene regulation that goes awry in cancer.…pthomsonApril 19, 2022 Read More
Publications of the Week Genome-Wide Analysis of Somatic Noncoding Mutation Patterns in CancerDietlein, F., et al. | April 13, 2022Numerous large-scale efforts have been undertaken to catalog and understand the biology of cancer-associated mutations…pthomsonApril 13, 2022 Read More
Publications of the Week Preclinical Modeling of Leiomyosarcoma Identifies Susceptibility to Transcriptional CDK Inhibitors through Antagonism of E2F-Driven Oncogenic Gene ExpressionHemming, M. L., et al. | April 12, 2022Leiomyosarcoma (LMS) is a neoplasm characterized by smooth muscle differentiation, complex copy-number alterations, tumor suppressor…pthomsonApril 12, 2022 Read More
Publications of the Week Types and Functions of Heterogeneity in MycobacteriaChung, E. S., et al. | April 8, 2022The remarkable ability of Mycobacterium tuberculosis to survive attacks from the host immune response and drug treatment…pthomsonApril 8, 2022 Read More
Publications of the Week Stitchr: Stitching Coding TCR Nucleotide Sequences from V/J/CDR3 InformationHeather, J. M., et al. | April 5, 2022The study and manipulation of T cell receptors (TCRs) is central to multiple fields across…pthomsonApril 5, 2022 Read More
Publications of the Week Orthogonally Induced Differentiation of Stem Cells for the Programmatic Patterning of Vascularized Organoids and Bioprinted TissuesSylar-Scott, M. A., et al. | April 1, 2022The generation of organoids and tissues with programmable cellular complexity, architecture and function would benefit…pthomsonApril 1, 2022 Read More
Publications of the Week HLA Autoimmune Risk Alleles Restrict the Hypervariable Region of T Cell ReceptorsIshigaki, K., et al. | March 30, 2022Polymorphisms in the human leukocyte antigen (HLA) genes strongly influence autoimmune disease risk. HLA risk alleles may…pthomsonMarch 30, 2022 Read More