Publications of the Week Somatic Mosaicism in Schizophrenia Brains Reveals Prenatal Mutational Processes Maury, E., et al. | November 18, 2024 Somatic mutations during brain development have been associated with several neurological disorders. Maury et al. performed…karnottNovember 18, 2024 Read More
Publications of the Week Brca1 Haploinsufficiency Promotes Early Tumor Onset and Epigenetic Alterations in a Mouse Model of Hereditary Breast Cancer Man-Chung Li, C., | November 15, 2024 Germline BRCA1 mutation carriers face a high breast cancer risk; however, the underlying mechanisms for this risk…karnottNovember 15, 2024 Read More
Publications of the Week Heterogeneous Genetic Architectures of Prostate Cancer Susceptibility in Sub-Saharan Africa Janivara, R., et al. | November 13, 2024 Men of African descent have the highest prostate cancer incidence and mortality rates, yet the…karnottNovember 13, 2024 Read More
Publications of the Week Immune Responses in Checkpoint Myocarditis Across Heart, Blood, and Tumour Blum, S., et al. | November 11, 2024 Immune checkpoint inhibitors are widely used anticancer therapies1 that can cause morbid and potentially fatal…karnottNovember 11, 2024 Read More
Publications of the Week SARS-CoV-2 XBB.1.5 mRNA Booster Vaccination Elicits Limited Mucosal Immunity Lasrado, N., et al. | November 5, 2024 mRNA vaccines for SARS-CoV-2 elicit robust antibody responses in the circulation, which aid in protection…karnottNovember 5, 2024 Read More
Publications of the Week Nuclear Release of eIF1 Restricts Start-Codon Selection During Mitosis Ly, J., et al. | November 4, 2024 Regulated start-codon selection has the potential to reshape the proteome through the differential production of…karnottNovember 4, 2024 Read More
Publications of the Week Anti-Viral Defence by an mRNA ADP-Ribosyltransferase That Blocks Translation Vassallo, C., et al. | November 1, 2024 Host-pathogen conflicts are crucibles of molecular innovation1,2. Selection for immunity to pathogens has driven the…karnottNovember 1, 2024 Read More
Publications of the Week AKT and EZH2 Inhibitors Kill TNBCs by Hijacking Mechanisms of Involution Schade, A., et al. | October 31, 2024 Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype and has the highest…karnottOctober 31, 2024 Read More
Publications of the Week Non-Pathogenic E. coli Displaying Decoy-Resistant IL18 Mutein Boosts Anti-Tumor and CAR NK Cell Responses Yang, S., et al. | October 28, 2024 This week, we profile a recent publication in Nature Biotechnology by Dr. Rizwan Romee from…karnottOctober 28, 2024 Read More
Publications of the Week Dopamine Dynamics Are Dispensable for Movement but Promote Reward Responses Cai, X., et al. | October 23, 2024 Dopamine signalling modes differ in kinetics and spatial patterns of receptor activation. How these modes…karnottOctober 23, 2024 Read More