Publications of the Week Cell Type-Specific Inference of Differential Expression in Spatial TranscriptomicsCable, D.M., et al. | September 9, 2022A central problem in spatial transcriptomics is detecting differentially expressed (DE) genes within cell types…sciencecitySeptember 9, 2022 Read More
Publications of the Week PD-L1 and PD-1 Expression in Pediatric Central Nervous System Germ Cell TumorsWoods, J.K., et al. | September 7, 2022Central nervous system (CNS) germ cell tumors (GCTs) represent 2-3% of all primary CNS tumors.…sciencecitySeptember 7, 2022 Read More
Publications of the Week Regulation of Neuroendocrine Plasticity by the RNA-Binding Protein ZFP36L1Chen, H.-Y., et al. | September 2, 2022Some small cell lung cancers (SCLCs) are highly sensitive to inhibitors of the histone demethylase…pthomsonSeptember 2, 2022 Read More
Publications of the Week Elucidating the Path to Plasmodium Prolyl-tRNA Synthetase Inhibitors That Overcome Halofuginone ResistanceTye, M. A., et al. | September 1, 2022The development of next-generation antimalarials that are efficacious against the human liver and asexual blood…pthomsonSeptember 1, 2022 Read More
Publications of the Week Evybactin Is a DNA Gyrase Inhibitor That Selectively Kills Mycobacterium tuberculosisImain, Y., et al. | August 26, 2022The antimicrobial resistance crisis requires the introduction of novel antibiotics. The use of conventional broad-spectrum…pthomsonAugust 26, 2022 Read More
Publications of the Week A Conserved Bacteroidetes Antigen Induces Anti-Inflammatory Intestinal T LymphocytesBousbaine, D., et al. | August 24, 2022The intestinal immune system can maintain tolerance to harmless stimuli such as commensal bacteria and…pthomsonAugust 24, 2022 Read More
Publications of the Week Pyramidal Neuron Subtype Diversity Governs Microglia States in the NeocortexStogsdill, J. A., et al. | August 19, 2022Microglia are specialized macrophages in the brain parenchyma that exist in multiple transcriptional states and…pthomsonAugust 19, 2022 Read More
Publications of the Week PI3K Drives the De Novo Synthesis of Coenzyme A from Vitamin B5Dibble, C. C, et al. | August 16, 2022This study was a collaboration between the laboratories of Dr. Christian C. Dibble and Dr.…pthomsonAugust 16, 2022 Read More
Publications of the Week Network Tau Spreading Is Vulnerable to the Expression Gradients of APOE and Glutamatergic-Related GenesMontal, V., et al. | August 12, 2022Intracellular Tau protein accumulation and spreading in the brain contribute to neurodegeneration and cognitive impairments…pthomsonAugust 12, 2022 Read More
Publications of the Week Polysaccharide and Conjugate Vaccines to Streptococcus pneumoniae Generate Distinct Humoral ResponsesDavies, L. R. L., et al. | August 11, 2022Streptococcus pneumoniae is a major cause of disease in older adults, for which two vaccines, a…pthomsonAugust 11, 2022 Read More