Publications of the Week

Fusion oncogenes can be cancer-defining molecular alterations that are essential for diagnosis and therapy selection.1,2…

Cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs) lack nanoscale structures essential for efficient…

Progressive decline of the adaptive immune system with increasing age coincides with a sharp increase…

KMT2C and KMT2D, encoding histone H3 lysine 4 methyltransferases, are among the most commonly mutated genes in…

Protein and vaccine therapies based on mRNA would benefit from an increase in translation capacity.…

Unlike other tumor types, existing immunotherapies have not proven very successful for pancreatic ductal adenocarcinoma…

Cancer vaccine development is inhibited by a lack of strategies for directing dendritic cell (DC)…

Persistent colonization and outgrowth of potentially pathogenic organisms in the intestine can result from long-term…

Mitochondrial loss and dysfunction drive T cell exhaustion, representing major barriers to successful T cell-based immunotherapies. Here,…

Placebo analgesia is a widely observed clinical phenomenon. Establishing a robust mouse model of placebo…