Publications of the Week Nociceptor-Immune Interactomes Reveal Insult-Specific Immune Signatures of Pain Jain, A., et al. | July 3, 2024 Inflammatory pain results from the heightened sensitivity and reduced threshold of nociceptor sensory neurons due…karnottJuly 3, 2024 Read More
Publications of the Week Longitudinal Humoral Analysis in RSV-Infected Infants Identifies Pre-existing RSV Strain-Specific G and Evolving Cross-Reactive F Antibodies Nziza, N., et al. | July 1, 2024 Respiratory syncytial virus (RSV) is among the most common causes of lower respiratory tract infection…karnottJuly 1, 2024 Read More
Publications of the Week Transient Growth Factor Expression via mRNA in Lipid Nanoparticles Promotes Hepatocyte Cell Therapy in Mice Smith, A., et al. | June 28, 2024 Primary human hepatocyte (PHH) transplantation is a promising alternative to liver transplantation, whereby liver function…karnottJune 28, 2024 Read More
Publications of the Week Botensilimab Plus Balstilimab in Relapsed/Refractory Microsatellite Stable Metastatic Colorectal Cancer: A Phase 1 Trial Bullock, A., et al. | June 27, 2024 Microsatellite stable metastatic colorectal cancer (MSS mCRC; mismatch repair proficient) has previously responded poorly to…karnottJune 27, 2024 Read More
Publications of the Week Strain-Specific Gut Microbial Signatures in Type 2 Diabetes Identified in a Cross-Cohort Analysis of 8,117 Metagenomes | June 26, 2024 The association of gut microbial features with type 2 diabetes (T2D) has been inconsistent due…karnottJune 26, 2024 Read More
Publications of the Week Defining Clinically Useful Biomarkers of Immune Checkpoint Inhibitors in Solid Tumors Holder, A.M., et al. | June 20, 2024 Although more than a decade has passed since the approval of immune checkpoint inhibitors (ICIs)…sciencecityJune 20, 2024 Read More
Publications of the Week Cell-Autonomous Role of Leucine-Rich Repeat Kinase in the Protection of Dopaminergic Neuron Survival Kang, J.K., et al. | June 18, 2024 Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common genetic cause of Parkinson's…sciencecityJune 18, 2024 Read More
Publications of the Week Efficient Site-Specific Integration of Large Genes in Mammalian Cells via Continuously Evolved Recombinases and Prime Editing Pandey, S., et al. | June 12, 2024 Methods for the targeted integration of genes in mammalian genomes suffer from low programmability, low…karnottJune 12, 2024 Read More
Publications of the Week The KAT Module of the Saga Complex Maintains the Oncogenic Gene Expression Program in MYCN-Amplified Neuroblastoma Malone, C., et al. | June 10, 2024 Pediatric cancers are frequently driven by genomic alterations that result in aberrant transcription factor activity.…karnottJune 10, 2024 Read More
Publications of the Week Viral Cis-Regulatory Elements As Sensors of Cellular States and Environmental Cues Rottenberg, J., et al. | June 4, 2024 To withstand a hostile cellular environment and replicate, viruses must sense, interpret, and respond to…karnottJune 4, 2024 Read More