Publications of the Week

Cancer cells edit gene expression to evade immunosurveillance. However, genome-wide studies of gene editing during…

Chromosome arm 8q is the most frequently gained chromosome arm in aneuploid prostate cancer and…

DNA polymerases are important drug targets, and many structural studies have captured them in distinct…

Achieving a reversible decrease of metabolism and other physiological processes in the whole organism, as…

Pathogenic bacteria secrete protein effectors to hijack host machinery and remodel their infectious niche. Rickettsia…

αβ T cell receptors (TCRs) principally recognize aberrant peptides bound to major histocompatibility complex molecules…

The choroid plexus (ChP) is a vital brain barrier and source of cerebrospinal fluid (CSF).…

Therapeutic small interfering RNA (siRNA) requires sugar and backbone modifications to inhibit nuclease degradation. However,…

KMT2C and KMT2D, encoding histone H3 lysine 4 methyltransferases, are among the most commonly mutated…

Although chimeric antigen receptor (CAR) T cell therapies have demonstrated promising clinical outcomes, durable remissions…