Publications of the Week Spatial Maps of T Cell Receptors and Transcriptomes Reveal Distinct Immune Niches and Interactions in the Adaptive Immune ResponseLiu, S., Iorgulescu, J. B., & Li, S., et al. | October 14, 2022T cells mediate antigen-specific immune responses to disease through the specificity and diversity of their…pthomsonOctober 14, 2022 Read More
Publications of the Week Differential ABC Transporter Expression during Hematopoiesis Contributes to Neutrophil-Biased Toxicity of Aurora Kinase InhibitorsChoul, D., et al. | October 13, 2022Drug-induced cytopenias are a prevalent and significant issue that worsens clinical outcomes and hinders the…pthomsonOctober 13, 2022 Read More
Publications of the Week Precise DNA Cleavage Using CRISPR-SpRYgestsChristie, K. A., et al. | October 7, 2022Methods for in vitro DNA cleavage and molecular cloning remain unable to precisely cleave DNA…pthomsonOctober 7, 2022 Read More
Publications of the Week Targeting Replication Stress in Cancer Therapyda Costa, A., et al. | October 7, 2022Replication stress is a major cause of genomic instability and a crucial vulnerability of cancer…pthomsonOctober 7, 2022 Read More
Publications of the Week CRISPR Screens in Drosophila Cells Identify Vsg as a Tc Toxin ReceptorXu, Y., et al. | September 30, 2022Entomopathogenic nematodes are widely used as biopesticides1,2. Their insecticidal activity depends on symbiotic bacteria such…pthomsonSeptember 30, 2022 Read More
Publications of the Week Developmental Dynamics of RNA Translation in the Human BrainDuffy, E. E., et al | September 30, 2022The precise regulation of gene expression is fundamental to neurodevelopment, plasticity and cognitive function. Although…pthomsonSeptember 30, 2022 Read More
Publications of the Week Organoid-on-a-Chip Model of Human ARPKD Reveals Mechanosensing Pathomechanisms for Drug DiscoveryHiratsuka, K., & Miyoshi, T., et al. | September 22, 2022Organoids serve as a novel tool for disease modeling in three-dimensional multicellular contexts. Static organoids,…pthomsonSeptember 22, 2022 Read More
Publications of the Week High-Performance Multiplex Drug-Gated CAR CircuitsLi, H.S., et al. | September 21, 2022Chimeric antigen receptor (CAR) T cells can revolutionize cancer medicine. However, overactivation, lack of tumor-specific…sciencecitySeptember 21, 2022 Read More
Publications of the Week A Bacterial Pan-Genome Makes Gene Essentiality Strain-Dependent and EvolvableRosconi, F. et al. | September 19, 2022Many bacterial species are represented by a pan-genome, whose genetic repertoire far outstrips that of…sciencecitySeptember 19, 2022 Read More
Publications of the Week Targeting Innate Immunity-Driven Inflammation in CKD and Cardiovascular DiseaseSpeer, T., et al. | September 14, 2022Mortality among patients with chronic kidney disease (CKD) is largely a consequence of cardiovascular disease…sciencecitySeptember 14, 2022 Read More