Publications of the Week Epstein–Barr Virus as a Leading Cause of Multiple Sclerosis: Mechanisms and ImplicationsBjornevik, K., et al. | February 13, 2023Epidemiological studies have provided compelling evidence that multiple sclerosis (MS) is a rare complication of…pthomsonFebruary 13, 2023 Read More
Publications of the Week Low Protease Activity in B Cell Follicles Promotes Retention of Intact Antigens After ImmunizationAung, A., et al. | February 10, 2023To generate protective immune responses, vaccine antigens are designed to mimic native protein structures on…pthomsonFebruary 10, 2023 Read More
Publications of the Week Encoding of Environmental Illumination by Primate Melanopsin NeuronsLiu,A., & Milner, E. S., et al. | February 7, 2023Light is an important environmental factor for most organisms because it regulates many physiological functions…pthomsonFebruary 7, 2023 Read More
Publications of the Week CRISPR Screens Reveal Genetic Determinants of PARP Inhibitor Sensitivity and Resistance in Prostate CancerTsujino, T., et al. | February 3, 2023Prostate cancer harboring BRCA1/2 mutations are often exceptionally sensitive to PARP inhibitors. However, genomic alterations in other…pthomsonFebruary 3, 2023 Read More
Publications of the Week In Vivo Dissection of Chamber-Selective Enhancers Reveals Estrogen-Related Receptor as a Regulator of Ventricular Cardiomyocyte IdentityCao, Y., et al. | February 2, 2023Cardiac chamber-selective transcriptional programs underpin the structural and functional differences between atrial and ventricular cardiomyocytes…pthomsonFebruary 2, 2023 Read More
Publications of the Week Cilia Function as Calcium-Mediated Mechanosensors That Instruct Left-Right AsymmetryDjenoune, L., & Mahamdeh, M., et al. | January 24, 2023Dr. Shiaulou Yuan's lab consists of a multidisciplinary group of biologists, biophysicists, and microscopists who…pthomsonJanuary 24, 2023 Read More
Publications of the Week CanB Is a Metabolic Mediator of Antibiotic Resistance in Neisseria gonorrhoeaeRubin, D. H. F., et al. | January 23, 2023Read the Publication This week we profile a recent publication in Nature Microbiology from the…pthomsonJanuary 23, 2023 Read More
Publications of the Week Assessing and Advancing the Safety of CRISPR-Cas Tools: From DNA to RNA EditingTao, J., et al. | January 19, 2023CRISPR-Cas gene editing has revolutionized experimental molecular biology over the past decade and holds great…pthomsonJanuary 19, 2023 Read More
Publications of the Week The Landscape of Tumor Cell States and Spatial Organization in H3-K27M Mutant Diffuse Midline Glioma Across Age and LocationLiu, I., Jiang, L., & Samuelsson, E. R., et al. | January 16, 2023Dr. Mariella Filbin's lab is interested in how pediatric brain tumors recapitulate certain aspects of…pthomsonJanuary 16, 2023 Read More
Publications of the Week Autoinhibitory Structure of Preligand Association State Implicates a New Strategy to Attain Effective DR5 Receptor ActivationDu, G. & Zhao, L., et al. | January 13, 2023Members of the tumor necrosis factor receptor superfamily (TNFRSF) are important therapeutic targets that can…pthomsonJanuary 13, 2023 Read More