Inflammation is an essential defense response but operates at the cost of normal tissue functions.…
karnottOctober 6, 2025
Acute leukemia requires precise molecular classification and urgent treatment. However, standard-of-care diagnostic tests are time-intensive…
karnottSeptember 29, 2025
Chimeric antigen receptor (CAR) T cells are highly effective in haematological malignancies1. However, progressive loss…
karnottSeptember 25, 2025
Prime editors make programmed genome modifications by writing new sequences into extensions of nicked DNA…
karnottSeptember 19, 2025
Loss-of-function variants in the lipid transporter ABCA7 substantially increase the risk of Alzheimer’s disease1,2, yet…
karnottSeptember 15, 2025
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive cognitive decline, yet its epigenetic…
karnottSeptember 12, 2025
Antibody–drug conjugates (ADCs) are effective targeted therapeutics but are limited in their ability to incorporate…
karnottSeptember 11, 2025
The awakening of dormant disseminated cancer cells appears to be responsible for the clinical relapses…
karnottSeptember 9, 2025
Chimeric antigen receptor (CAR) T cell therapy targeting CD19 elicits remarkable clinical efficacy in B…
karnottSeptember 4, 2025
