Publications of the Week Irisin Reduces Amyloid-β by Inducing the Release of Neprilysin from Astrocytes Following Downregulation of Erk-STAT3 SignalingKim, E., et al. | September 14, 2023A pathological hallmark of Alzheimer’s disease (AD) is the deposition of amyloid-β (Aβ) protein in…pthomsonSeptember 14, 2023 Read More
Publications of the Week Airway Stem Cell Reconstitution by the Transplantation of Primary or Pluripotent Stem Cell-Derived Basal CellsMa, L., et al. | September 11, 2023Life-long reconstitution of a tissue’s resident stem cell compartment with engrafted cells has the potential…sciencecitySeptember 11, 2023 Read More
Publications of the Week Photopolymerizable Hydrogel for Enhanced Intramyocardial Vascular Progenitor Cell Delivery and Post-Myocardial Infarction HealingHong, X., et al. | September 7, 2023Cell transplantation success for myocardial infarction (MI) treatment is often hindered by low engraftment due…sciencecitySeptember 7, 2023 Read More
Publications of the Week Brain-Region-Specific Changes in Neurons and Glia and Dysregulation of Dopamine Signaling in Grin2a Mutant MiceFarsi, Z., et al. | September 5, 2023A genetically valid animal model could transform our understanding of schizophrenia (SCZ) disease mechanisms. Rare…sciencecitySeptember 5, 2023 Read More
Publications of the Week A Novel Molecular Class That Recruits HDAC/MECP2 Complexes to PU.1 Motifs Reduces NeuroinflammationRalvenius, W., et al. | August 30, 2023Pervasive neuroinflammation occurs in many neurodegenerative diseases, including Alzheimer’s disease (AD). SPI1/PU.1 is a transcription…sciencecityAugust 30, 2023 Read More
Publications of the Week Glucose Oxidation-Dependent Survival of Activated B Cells Provides a Putative Novel Therapeutic Target for Lupus TreatmentWilson, J., et al. | August 29, 2023Aberrant metabolic demand is observed in immune/inflammatory disorders, yet the role in pathogenesis remains unclear.…sciencecityAugust 29, 2023 Read More
Publications of the Week Metagenomic Profiling Pipelines Improve Taxonomic Classification for 16S Amplicon Sequencing DataOdom, A., et al. | August 28, 2023Most experiments studying bacterial microbiomes rely on the PCR amplification of all or part of…sciencecityAugust 28, 2023 Read More
Publications of the Week Elevation of IL-17 Cytokines Distinguishes Kawasaki Disease from Other Pediatric Inflammatory DisordersBrodeur, K., et al. | August 25, 2023Kawasaki disease (KD) is a systemic vasculitis of young children that can lead to development…sciencecityAugust 25, 2023 Read More
Publications of the Week A Zpr1 Co-chaperone Mediates Folding of Eukaryotic Translation Elongation Factor 1A via a GTPase CycleMcQuown, A., et al. | August 24, 2023General protein folding is mediated by chaperones that utilize ATP hydrolysis to regulate client binding…sciencecityAugust 24, 2023 Read More
Publications of the Week KDM6A Epigenetically Regulates Subtype Plasticity in Small Cell Lung CancerDuplaquet, L., et al. | August 22, 2023Small cell lung cancer (SCLC) exists broadly in four molecular subtypes: ASCL1, NEUROD1, POU2F3 and…pthomsonAugust 22, 2023 Read More