Publications of the Week In Vivo Prime Editing Rescues Alternating Hemiplegia of Childhood in Mice Sousa, A., et al. | August 4, 2025 Alternating hemiplegia of childhood (AHC) is a neurodevelopmental disorder with no disease-modifying treatment. Mutations in…karnottAugust 4, 2025 Read More
Publications of the Week Single-Cell Image-Based Screens Identify Host Regulators of Ebola Virus Infection Dynamics Carlson, R., et al. | July 30, 2025 Filoviruses such as Ebola virus (EBOV) give rise to frequent epidemics with high case fatality…karnottJuly 30, 2025 Read More
Publications of the Week Brain Endothelial Gap Junction Coupling Enables Rapid Vasodilation Propagation During Neurovascular Coupling Krolak, T., et al. | July 28, 2025 To meet the brain’s moment-to-moment energy demand, neural activation rapidly increases local blood flow. This…karnottJuly 28, 2025 Read More
Publications of the Week Germline Genetic Variation Impacts Clonal Hematopoiesis Landscape and Progression to Malignancy Liu, J., et al. | July 23, 2025 With age, clonal expansions occur pervasively across normal tissues yet only in rare instances lead…karnottJuly 23, 2025 Read More
Publications of the Week CellLENS Enables Cross-Domain Information Fusion for Enhanced Cell Population Delineation in Single-Cell Spatial Omics Data Zhu, B., et al. | July 22, 2025 Delineating cell populations is crucial for understanding immune function in health and disease. Spatial omics…karnottJuly 22, 2025 Read More
Publications of the Week A Multi-Adjuvant Personal Neoantigen Vaccine Generates Potent Immunity in Melanoma Blass, E., et al. | July 17, 2025 Personalized neoantigen-targeting vaccines have demonstrated great promise; however, improved immunogenicity is still needed. Since antigen…karnottJuly 17, 2025 Read More
Publications of the Week Plasma Exosomes in Insulin Resistant Obesity Exacerbate Progression of Triple Negative Breast Cancer Llévenes, P., et al. | July 14, 2025 Breast cancer, the most common cancer among women worldwide, continues to pose significant public health…karnottJuly 14, 2025 Read More
Publications of the Week CellLENS Enables Cross-Domain Information Fusion for Enhanced Cell Population Delineation in Single-Cell Spatial Omics Data Zhu, B., et al. | July 9, 2025 Delineating cell populations is crucial for understanding immune function in health and disease. Spatial omics…karnottJuly 9, 2025 Read More
Publications of the Week Intrinsically Weak Sex Chromosome Drive Through Sequential Asymmetric Meiosis Meng, X., et al. | July 8, 2025 Meiotic drivers are selfish genetic elements that bias their own transmission, violating Mendel’s Law of…karnottJuly 8, 2025 Read More
Publications of the Week Neoadjuvant PD-1 and PD-L1 Blockade With Chemotherapy for Borderline Resectable and Unresectable Stage III Non–Small Cell Lung Cancer Ricciuti, B., et al. | July 4, 2025 Is neoadjuvant programmed cell death 1 protein (PD-1) or programmed cell death 1 ligand 1…karnottJuly 4, 2025 Read More