Publications of the Week

Emerging evidence indicates that splicing factors mediate the close link between transcription and splicing. However,…

Microscopic colitis (MC) is a chronic inflammatory disease of the large intestine and a common…

Lymphatic muscle cells (LMCs) are indispensable for lymphatic vessel contraction, and their aberrant recruitment or…

Mitochondria play a vital role in cellular energy metabolism and vascular health, with their function…

Aortic aneurysms are potentially fatal focal enlargements of the aortic lumen; the disease burden is…

Repeat element viral mimicry is a common feature in pancreatic ductal adenocarcinoma (PDAC) that requires…

A major contributor to poor sensitivity to anti-cancer kinase inhibitor therapy is drug-induced cellular adaptation,…

Integrator (INT) is a metazoan-specific complex that targets promoter-proximally paused RNA polymerase II (RNAPII) for…

The composition and organization of the cell surface determine how cells interact with their environment.…

In a therapeutic context, supraphysiological expression of transgenes can compromise engineered phenotypes and lead to…