Publications of the Week Germline Genetic Variation Impacts Clonal Hematopoiesis Landscape and Progression to Malignancy Liu, J., et al. | July 23, 2025 With age, clonal expansions occur pervasively across normal tissues yet only in rare instances lead…karnottJuly 23, 2025 Read More
Publications of the Week CellLENS Enables Cross-Domain Information Fusion for Enhanced Cell Population Delineation in Single-Cell Spatial Omics Data Zhu, B., et al. | July 22, 2025 Delineating cell populations is crucial for understanding immune function in health and disease. Spatial omics…karnottJuly 22, 2025 Read More
Publications of the Week A Multi-Adjuvant Personal Neoantigen Vaccine Generates Potent Immunity in Melanoma Blass, E., et al. | July 17, 2025 Personalized neoantigen-targeting vaccines have demonstrated great promise; however, improved immunogenicity is still needed. Since antigen…karnottJuly 17, 2025 Read More
Publications of the Week Plasma Exosomes in Insulin Resistant Obesity Exacerbate Progression of Triple Negative Breast Cancer Llévenes, P., et al. | July 14, 2025 Breast cancer, the most common cancer among women worldwide, continues to pose significant public health…karnottJuly 14, 2025 Read More
Publications of the Week CellLENS Enables Cross-Domain Information Fusion for Enhanced Cell Population Delineation in Single-Cell Spatial Omics Data Zhu, B., et al. | July 9, 2025 Delineating cell populations is crucial for understanding immune function in health and disease. Spatial omics…karnottJuly 9, 2025 Read More
Publications of the Week Intrinsically Weak Sex Chromosome Drive Through Sequential Asymmetric Meiosis Meng, X., et al. | July 8, 2025 Meiotic drivers are selfish genetic elements that bias their own transmission, violating Mendel’s Law of…karnottJuly 8, 2025 Read More
Publications of the Week Neoadjuvant PD-1 and PD-L1 Blockade With Chemotherapy for Borderline Resectable and Unresectable Stage III Non–Small Cell Lung Cancer Ricciuti, B., et al. | July 4, 2025 Is neoadjuvant programmed cell death 1 protein (PD-1) or programmed cell death 1 ligand 1…karnottJuly 4, 2025 Read More
Publications of the Week Single-Cell and Spatial Transcriptomics of Stricturing Crohn’s Disease Highlights a Fibrosis-Associated Network Kong, L., et al. | July 2, 2025 Fibrosis is a major complication of Crohn’s disease (CD) marked by excess deposition of extracellular…karnottJuly 2, 2025 Read More
Publications of the Week ZNF280A Links DNA Double-Strand Break Repair to Human 22q11.2 Distal Deletion Syndrome Clarke, T., et al. | June 26, 2025 DNA double-strand breaks (DSB) are among the most deleterious forms of DNA damage and, if…karnottJune 26, 2025 Read More
Publications of the Week Perturb-Multimodal: A Platform for Pooled Genetic Screens With Imaging and Sequencing in Intact Mammalian Tissue Saunders, R., et al. | June 23, 2025 Metazoan life requires the coordinated activities of thousands of genes in spatially organized cell types.…karnottJune 23, 2025 Read More