Publications of the Week Protective Renalase-Deficiency in Beta Cells Shapes Immune Metabolism and Function in Autoimmune DiabetesBode, K., et al. | May 25, 2023Type 1 diabetes (T1D) is caused by the immune-mediated loss of pancreatic beta cells that…pthomsonMay 25, 2023 Read More
Publications of the Week Dynamic BH3 Profiling Identifies Pro-Apoptotic Drug Combinations for the Treatment of Malignant Pleural MesotheliomaPotter, D. S., et al. | May 24, 2023Malignant pleural mesothelioma (MPM) has relatively ineffective first/second-line therapy for advanced disease and only 18%…pthomsonMay 24, 2023 Read More
Publications of the Week Atrophy in Behavioral Variant Frontotemporal Dementia Spans Multiple Large-Scale Prefrontal and Temporal NetworksEldaief, M. C., et al. | May 19, 2023The identification of a neurodegenerative disorder’s distributed pattern of atrophy—or atrophy “signature”— can lend insights…pthomsonMay 19, 2023 Read More
Publications of the Week ERα-Associated Translocations Underlie Oncogene Amplifications in Breast CancerLee, J., et al. | May 18, 2023Focal copy-number amplification is an oncogenic event. Although recent studies have revealed the complex structure1,2,3 and…pthomsonMay 18, 2023 Read More
Publications of the Week Autologous Neutralizing Antibodies Increase with Early Antiretroviral Therapy and Shape HIV Rebound after Treatment InterruptionEsmaeilzadeh, E., et al. | May 12, 2023Early initiation of antiretroviral therapy (ART) alters viral rebound kinetics after analytic treatment interruption (ATI)…pthomsonMay 12, 2023 Read More
Publications of the Week Abundant Aβ Fibrils in Ultracentrifugal Supernatants of Aqueous Extracts from Alzheimer’s Disease BrainsStern, A. M., et al. | May 11, 2023Soluble oligomers of amyloid β-protein (Aβ) have been defined as aggregates in supernatants following ultracentrifugation…pthomsonMay 11, 2023 Read More
Publications of the Week Trehalose-Guanosine Glycopolymer Hydrogels Direct Adaptive Glia Responses in CNS InjuryDuBois, E. M., et al. | May 5, 2023Neural tissue damaged after central nervous system (CNS) injury does not naturally regenerate but is…pthomsonMay 5, 2023 Read More
Publications of the Week Dynamic Changes in Heparan Sulfate Nanostructure in Human Pluripotent Stem Cell DifferentiationAl Mahbuba, D., et al. | May 2, 2023The Kiessling Group uses chemical biology to elucidate the biological roles of carbohydrates, with a…pthomsonMay 2, 2023 Read More
Publications of the Week Cross-Modal Autoencoder Framework Learns Holistic Representations of Cardiovascular StateRadhakrishnan, A., et al. | April 28, 2023A fundamental challenge in diagnostics is integrating multiple modalities to develop a joint characterization of…pthomsonApril 28, 2023 Read More
Publications of the Week Mini-PCDH15 Gene Therapy Rescues Hearing in a Mouse Model of Usher Syndrome Type 1FIvanchenko, M., et al. | April 28, 2023Usher syndrome type 1 F (USH1F), caused by mutations in the protocadherin-15 gene (PCDH15), is characterized…pthomsonApril 28, 2023 Read More