Publications of the Week IL-33 Signaling Alters Regulatory T Cell Diversity in Support of Tumor Development Li, A., et al. | December 20, 2019 Regulatory T cells (Tregs) can impair anti-tumor immune responses and are associated with poor prognosis in…sciencecityDecember 20, 2019 Read More
Publications of the Week Domain-specific Quantification of Prion Protein in Cerebrospinal Fluid by Targeted Mass Spectrometry Minikel, E., V., et al | December 20, 2019 Therapies currently in preclinical development for prion disease seek to lower prion protein (PrP) expression…sciencecityDecember 20, 2019 Read More
Publications of the Week A Strategic Approach for Fluorescence Imaging of Membrane Proteins in a Native-like Environment Swiecicki, J., M., et al. | December 20, 2019 Biological membranes are complex barriers in which membrane proteins and thousands of lipidic species participate…sciencecityDecember 20, 2019 Read More
Publications of the Week Toward a Common Coordinate Framework for the Human Body Rood, E., J., et al. | December 19, 2019 Understanding the genetic and molecular drivers of phenotypic heterogeneity across individuals is central to biology.…sciencecityDecember 19, 2019 Read More
Publications of the Week Activity-by-Contact Model of Enhancer–Promoter Regulation from Thousands of CRISPR Perturbations Fulco, P., C., et al. | December 11, 2019 Enhancer elements in the human genome control how genes are expressed in specific cell types…sciencecityDecember 11, 2019 Read More
Publications of the Week Single Cell Census of Human Kidney Organoids Shows Reproducibility and Diminished Off-Target Cells after Transplantation Subramanian, A., et al. | December 11, 2019 Human iPSC-derived kidney organoids have the potential to revolutionize discovery, but assessing their consistency and…sciencecityDecember 11, 2019 Read More
Publications of the Week Somatic and Dendritic Encoding of Spatial Variables in Retrosplenial Cortex Differs during 2D Navigation Voigts, J., et al. | December 11, 2019 Active amplification of organized synaptic inputs in dendrites can endow individual neurons with the ability…sciencecityDecember 11, 2019 Read More
Publications of the Week Engineering, Delivery, and Biological Validation of Artificial microRNA Clusters for Gene Therapy Applications Science in Boston | December 9, 2019 MicroRNAs are tiny RNAs belonging to the larger family of non coding RNAs (i.e. genes…sciencecityDecember 9, 2019 Read More
Publications of the Week Neural Circuits for Evidence Accumulation and Decision Making in Larval Zebrafish Bahl, A., et al. | December 6, 2019 To make appropriate decisions, animals need to accumulate sensory evidence. Simple integrator models can explain…sciencecityDecember 6, 2019 Read More
Publications of the Week Immune Recognition of Microbial Metabolites Garrett, W.S. | December 3, 2019 Mucosal immunology research continues its fascination with microbial metabolites. In 2019, researchers uncovered extended functions…sciencecityDecember 3, 2019 Read More