Publications of the Week Genotype-Fitness Maps of EGFR-Mutant Lung Adenocarcinoma Chart the Evolutionary Landscape of Resistance for Combination Therapy Optimization Bolan, P., O., et al. | October 30, 2019 Cancer evolution poses a central obstacle to cure, as resistant clones expand under therapeutic selection…sciencecityOctober 30, 2019 Read More
Publications of the Week Fibroblastic Reticular Cells Enhance T Cell Metabolism and Survival via Epigenetic Remodeling Brown, F., D., et al. | October 28, 2019 Lymph node fibroblastic reticular cells (FRCs) respond to signals from activated T cells by releasing…sciencecityOctober 28, 2019 Read More
Publications of the Week A Rapid Triage Test for Active Pulmonary Tuberculosis in Adult Patients with Persistent Cough Ahmad, R., et al. | October 28, 2019 Tuberculosis remains a global health burden. Ahmad et al. used machine learning to develop an algorithm…sciencecityOctober 28, 2019 Read More
Publications of the Week Cell Swelling, Softening and Invasion in a Three-Dimensional Breast Cancer Model Han, Y., H., et al. | October 24, 2019 Control of the structure and function of three-dimensional multicellular tissues depends critically on the spatial…sciencecityOctober 24, 2019 Read More
Publications of the Week Unique Structural Features in an Nramp Metal Transporter Impart Substrate-Specific Proton Cotransport and a Kinetic Bias to Favor Import Bozzi, A., T., et al. | October 21, 2019 Natural resistance-associated macrophage protein (Nramp) transporters enable uptake of essential transition metal micronutrients in numerous…sciencecityOctober 21, 2019 Read More
Publications of the Week Optical Pooled Screens in Human Cells Feldman, D., et al. | October 18, 2019 Genetic screens are critical for the systematic identification of genes underlying cellular phenotypes. Pooling gene…sciencecityOctober 18, 2019 Read More
Publications of the Week Bacterial Variability in the Mammalian Gut Captured by a Single-Cell Synthetic Oscillator Riglar, D., T., et al. | October 15, 2019 Synthetic gene oscillators have the potential to control timed functions and periodic gene expression in…sciencecityOctober 15, 2019 Read More
Publications of the Week Structural Basis for the Docking of mTORC1 on the Lysosomal Surface Rogala, K.,B., et al. | October 14, 2019 The mTORC1 protein kinase regulates growth in response to nutrients and growth factors. Nutrients promote…sciencecityOctober 14, 2019 Read More
Publications of the Week A Luminal Unfolding Microneedle Injector for Oral Delivery of Macromolecules Salvador, E., C., et al. | October 11, 2019 We developed an ingestible system capable of applying small micro-needle patches in the small intestine…sciencecityOctober 11, 2019 Read More
Publications of the Week Phototherapy and Extracorporeal Membrane Oxygenation Facilitate Removal of Carbon Monoxide in Rats Zazzeron, L., et al. | October 11, 2019 Carbon monoxide (CO) is a colorless, odorless gas that can cause severe illness and death…sciencecityOctober 11, 2019 Read More