Publications of the Week T Lymphocytes and Cytotoxic Astrocyte Blebs Correlate Across Autism Brains DiStasio, M., M., et al. | November 15, 2019 Autism spectrum disorder (ASD) affects 1 in 59 children, yet except for rare genetic causes,…sciencecityNovember 15, 2019 Read More
Publications of the Week Retro-2 Protects Cells from Ricin Toxicity by Inhibiting ASNA1-Mediated Er Targeting and Insertion of Tail-Anchored Proteins Morgens, D., W., et al. | November 13, 2019 The small molecule Retro-2 prevents ricin toxicity through a poorly-defined mechanism of action (MOA), which…sciencecityNovember 13, 2019 Read More
Publications of the Week Inducible Histone K-to-M Mutations Are Dynamic Tools to Probe the Physiological Role of Site-Specific Histone Methylation In Vitro and In Vivo Brumbaugh, J., et al. | November 8, 2019 Development and differentiation are associated with profound changes to histone modifications, yet their in vivo…sciencecityNovember 8, 2019 Read More
Publications of the Week A Generalized HIV Vaccine Design Strategy for Priming of Broadly Neutralizing Antibody Responses Steichen, J., M., et al. | November 7, 2019 Vaccine induction of broadly neutralizing antibodies (bnAbs) to human immunodeficiency virus (HIV) remains a major…sciencecityNovember 7, 2019 Read More
Publications of the Week Genotype-Fitness Maps of EGFR-Mutant Lung Adenocarcinoma Chart the Evolutionary Landscape of Resistance for Combination Therapy Optimization Bolan, P., O., et al. | October 30, 2019 Cancer evolution poses a central obstacle to cure, as resistant clones expand under therapeutic selection…sciencecityOctober 30, 2019 Read More
Publications of the Week Fibroblastic Reticular Cells Enhance T Cell Metabolism and Survival via Epigenetic Remodeling Brown, F., D., et al. | October 28, 2019 Lymph node fibroblastic reticular cells (FRCs) respond to signals from activated T cells by releasing…sciencecityOctober 28, 2019 Read More
Publications of the Week A Rapid Triage Test for Active Pulmonary Tuberculosis in Adult Patients with Persistent Cough Ahmad, R., et al. | October 28, 2019 Tuberculosis remains a global health burden. Ahmad et al. used machine learning to develop an algorithm…sciencecityOctober 28, 2019 Read More
Publications of the Week Cell Swelling, Softening and Invasion in a Three-Dimensional Breast Cancer Model Han, Y., H., et al. | October 24, 2019 Control of the structure and function of three-dimensional multicellular tissues depends critically on the spatial…sciencecityOctober 24, 2019 Read More
Publications of the Week Unique Structural Features in an Nramp Metal Transporter Impart Substrate-Specific Proton Cotransport and a Kinetic Bias to Favor Import Bozzi, A., T., et al. | October 21, 2019 Natural resistance-associated macrophage protein (Nramp) transporters enable uptake of essential transition metal micronutrients in numerous…sciencecityOctober 21, 2019 Read More
Publications of the Week Optical Pooled Screens in Human Cells Feldman, D., et al. | October 18, 2019 Genetic screens are critical for the systematic identification of genes underlying cellular phenotypes. Pooling gene…sciencecityOctober 18, 2019 Read More