Publications of the Week Functionally Uncoupled Transcription–Translation in Bacillus subtilis Johnson, G.E., et al. | September 7, 2020 Transcription-translation coupling has long been considered a defining feature of the central dogma in bacteria.…eabramovichSeptember 7, 2020 Read More
Publications of the Week A Single Human VH-gene Allows for a Broad-Spectrum Antibody Response Targeting Bacterial Lipopolysaccharides in the Blood Sangesland, M., et al. | September 4, 2020 B cell receptors (BCRs) display a combination of variable (V)-gene-encoded complementarity determining regions (CDRs) and…eabramovichSeptember 4, 2020 Read More
Publications of the Week Enhancer Dependence of Cell-Type–Specific Gene Expression Increases with Developmental Age Cai, W., et al. | September 2, 2020 Gene regulatory logic reflects the occupancy of cis elements by transcription factors and the configuration of promoters…eabramovichSeptember 2, 2020 Read More
Publications of the Week Engineering Designer Beta Cells with a CRISPR-Cas9 Conjugation Platform Lim, D., et al. | August 28, 2020 The authors developed a convenient platform to conjugate molecules to Cas9, and using this platform…eabramovichAugust 28, 2020 Read More
Publications of the Week Novel Antimicrobials from Uncultured Bacteria Acting against Mycobacterium tuberculosis Quigley, J., et al. | August 26, 2020 Decreasing discovery rates and increasing resistance have underscored the need for novel therapeutic options to…eabramovichAugust 26, 2020 Read More
Publications of the Week Engineered PLGA Microparticles for Long-Term, Pulsatile Release of STING Agonist for Cancer Immunotherapy Lu, X., et al. | August 24, 2020 STING agonist – a cancer immunotherapeutic drug – could produce strong antitumor immune responses, but…eabramovichAugust 24, 2020 Read More
Publications of the Week A Distinct Transcriptional Program in Human CAR T Cells Bearing the 4-1BB Signaling Domain Revealed by scRNA-Seq Boroughs, A.C., et al. | August 21, 2020 The authors looked at the full transcriptional profile of CAR T cells bearing different signaling…eabramovichAugust 21, 2020 Read More
Publications of the Week A Switch in p53 Dynamics Marks Cells that Escape from DSB-Induced Cell Cycle Arrest Tsabar, M., et al. | August 19, 2020 In response to DNA damage induced by ionizing irradiation, p53 undergoes oscillatory dynamics with a…eabramovichAugust 19, 2020 Read More
Publications of the Week Epigenetic Transcriptional Reprogramming by WT1 Mediates a Repair Response during Podocyte Injury Ettou, S., et al. | August 17, 2020 The authors examined transcriptional reprogramming during podocyte injury. Podocytes are crucial for maintaining filtration in…eabramovichAugust 17, 2020 Read More
Publications of the Week Epigenetic Regulator Function through Mouse Gastrulation Grosswendt, S., et al. | August 13, 2020 During ontogeny, proliferating cells become restricted in their fate through the combined action of cell-type-specific…eabramovichAugust 13, 2020 Read More