Publications of the Week Cell Type-Specific Lipid Storage Changes in Parkinson’s Disease Patient Brains Are Recapitulated by Experimental Glycolipid Disturbance Brekk, O.R., et al. | November 5, 2020 This study identified a unique lipid signature in human post-mortem Parkinson’s disease brain, wherein lipids…eabramovichNovember 5, 2020 Read More
Publications of the Week Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors Richters, A., et al. | November 2, 2020 In pursuit of mechanistically novel modulators of androgen receptor, the authors have discovered a potent,…eabramovichNovember 2, 2020 Read More
Publications of the Week GATA6 Mutations in hiPSCs Inform Mechanisms for Maldevelopment of the Heart, Pancreas, and Diaphragm Sharma, A., et al. | October 29, 2020 In collaboration with the NIH’s Pediatric Cardiac Genomics Consortium, the authors sequenced thousands of children…eabramovichOctober 29, 2020 Read More
Publications of the Week Augmenting Emergency Granulopoiesis with CpG Conditioned Mesenchymal Stromal Cells in Murine Neutropenic Sepsis Ng, J., et al. | October 28, 2020 Emergency granulopoiesis, or the de novo generation of neutrophils in response to a systemic infection…eabramovichOctober 28, 2020 Read More
Publications of the Week Persistence and Decay of Human Antibody Responses to the Receptor Binding Domain of SARS-CoV-2 Spike Protein in COVID-19 Patients Iyer, A.S., et al. | October 26, 2020 The authors show that antibody responses to the receptor binding domain of the spike protein…eabramovichOctober 26, 2020 Read More
Publications of the Week Extracellular Matrix Plasticity as a Driver of Cell Spreading Grolman, J.M., et al. | October 23, 2020 In many biomaterial systems, plastic deformation of extracellular matrix, degradation, or relaxation of stress are…eabramovichOctober 23, 2020 Read More
Publications of the Week Absence of Survival and Motor Deficits in 500 Repeat C9ORF72 BAC Mice Mordes, D.A., et al. | October 22, 2020 A hexanucleotide repeat expansion at C9ORF72 is the most common genetic cause of amyotrophic lateral…eabramovichOctober 22, 2020 Read More
Publications of the Week Parallel Single-Cell RNA-Seq and Genetic Recording Reveals Lineage Decisions in Developing Embryoid Bodies Kim, I.S., et al. | October 21, 2020 Early developmental specification can be modeled by differentiating embryonic stem cells (ESCs) to embryoid bodies…eabramovichOctober 21, 2020 Read More
Publications of the Week A Stearoyl-CoA Desaturase Inhibitor Prevents Multiple Parkinson’s Disease-Phenotypes in α-Synuclein Mice Nuber, S., et al. | October 14, 2020 The α-synuclein protein accumulates in Parkinson’s disease and other synucleinopathies. Growing evidence suggests that lipid-rich…eabramovichOctober 14, 2020 Read More
Publications of the Week Association of Caffeine and Related Analytes with Resistance to Parkinson’s Disease among LRRK2 Mutation Carriers: A Metabolomic Study Crotty, G. F., et al. | October 12, 2020 This study observed that caffeine and its related analytes were lower in individuals with Parkinson's…eabramovichOctober 12, 2020 Read More