Publications of the Week Local Externalization of Phosphatidylserine Mediates Developmental Synaptic Pruning by Microglia Scott-Hewitt, N., et al. | July 23, 2020 Neuronal circuit assembly requires the fine balance between synapse formation and elimination. Microglia, through the…eabramovichJuly 23, 2020 Read More
Publications of the Week Single-Cell Lineage Tracing Unveils a Role for TCF15 in Haematopoiesis Rodriguez-Fraticelli, A.E., et al. | July 21, 2020 Bone marrow transplantation therapy relies on the life-long regenerative capacity of haematopoietic stem cells (HSCs)1,2.…eabramovichJuly 21, 2020 Read More
Publications of the Week Systematic Quantitative Analysis of Ribosome Inventory During Nutrient Stress An, H., et al. | July 17, 2020 Mammalian cells reorganize their proteomes in response to nutrient stress through translational suppression and degradative…eabramovichJuly 17, 2020 Read More
Publications of the Week The Evolutionarily Conserved piRNA-Producing Locus pi6 Is Required for Male Mouse Fertility Wu, PH., et al. | July 14, 2020 The results suggest that in mammals — including human beings — a convoluted network of…eabramovichJuly 14, 2020 Read More
Publications of the Week An Ecological Framework to Understand the Efficacy of Fecal Microbiota Transplantation Xiao, Y., et al. | July 10, 2020 The authors present an ecological framework to understand the efficacy of fecal microbiota transplantation (FMT)…eabramovichJuly 10, 2020 Read More
Publications of the Week Sex Differences in Gene Expression and Regulatory Networks across 29 Human Tissues Lopes-Ramos, C.M., et al. | July 7, 2020 The authors modeled the network of factors that control gene expression and observed that these…eabramovichJuly 7, 2020 Read More
Publications of the Week Tau Molecular Diversity Contributes to Clinical Heterogeneity in Alzheimer’s Disease Dujardin, S., et al. | July 3, 2020 Alzheimer’s disease (AD) causes unrelenting, progressive cognitive impairments, but its course is heterogeneous, with a…eabramovichJuly 3, 2020 Read More
Publications of the Week The Role of Bone Morphogenetic Protein Signaling in Non-Alcoholic Fatty Liver Disease Thayer, T.E., et al. | July 2, 2020 Despite the growing burden and high morbidity and mortality associated with non-alcoholic fatty liver disease…eabramovichJuly 2, 2020 Read More
Publications of the Week Drug GRADE: An Integrated Analysis of Population Growth and Cell Death Reveals Drug-Specific and Cancer Subtype-Specific Response Profiles Schwartz, H.R., et al. | June 29, 2020 The typical measurement for evaluating drugs doesn’t distinguish between responses that are due to inhibition…eabramovichJune 29, 2020 Read More
Publications of the Week cGMP via PKG Activates 26S Proteasomes and Enhances Degradation of Proteins, Including Ones that Cause Neurodegenerative Diseases VerPlank, J.J.S., et al. | June 26, 2020 The authors demonstrate that agents that raise cGMP and activate the cGMP-dependent protein kinase (PKG),…eabramovichJune 26, 2020 Read More